Stiff-person syndrome (SPS) is characterised by progressive rigidity and muscle spasms
affecting the axial and limb muscles. Since its initial description in 1956, marked progress …

Opinion statement Stiff person syndrome (SPS) varies from mild to severe, but if untreated it
can be progressive and disabling. Although progress has been made in understanding and …

Stiff person syndrome (SPS) is an autoimmune CNS disorder characterized by muscle
rigidity, spasms and anxiety. The majority of patients have high-titer autoantibodies (ab) …

Spinal-generated movement disorders (SGMDs) include spinal segmental myoclonus,
propriospinal myoclonus, orthostatic tremor, secondary paroxysmal dyskinesias, stiff person …

Background The clinical spectrum of stiff-person syndrome (SPS) encompasses a wide
range of signs including psychiatric symptoms (PS). Objective Our objective was to provide …

Stiff person syndrome (SPS), stiff limb syndrome, jerking SPS and progressive
encephalomyelitis with rigidity and myoclonus (PERM) are a family of rare, insidiously …

Background Anxiety is a heterogeneous behavioral domain playing a role in a variety of
neuropsychiatric diseases. While anxiety is the cardinal symptom in disorders such as panic …

Several neurological syndromes have been recognized associated to GAD antibodies.
Among those disorders, cerebellar ataxia (CA) is one of the most common, along with stiff …

Advances in the clinical diagnosis, prognosis, pathogenesis, and therapies for stiff person
syndrome (SPS), based on observations in more than 50 consecutive patients, are …

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the central
nervous system. This paper reviews the current knowledge derived from positron emission …