OBJECTIVE To develop a topical sildenafil hydrogel and evaluate its effect on wound
healing in dogs. ANIMALS 6 purpose-bred, sexually intact, adult Beagles. PROCEDURES …

To develop sildenafil lactate, a salt form of sildenafil with improved solubility and
bioavailability of poorly water-soluble sildenafil base, this salt form was prepared using a …

In this work we provided a selective, sensitive and rapid HPLC-UV method for quantification
of sildenafil in human plasma. We have adopted a simple liquid–liquid extraction procedure …

Sildenafil (SDL) is a phosphodiesterase type 5 inhibitor and it is approved for the treatment
of erectile dysfunction and pulmonary hypertension. SDL is extensively metabolized to its …

A simple, rapid, specific and reliable UFLC coupled with ESI‐MSMS assay method to
simultaneously quantify sildenafil and N‐desmethyl sildenafil, with loperamide as internal …

To develop a sildenafil lactate-loaded orally disintegrating tablet with a faster drug effect
onset and immediate action of erection, the orally disintegrating tablets were prepared with …

This study was conducted to compare dissolution profiles of four Jordanian registered
sildenafil (SDF) products to the originator. Dissolution samples were analyzed utilizing a …

Due to the widespread use of sildenafil, the market is full of different counterfeited
preparations that contain either an unknown amount of sildenafil or mixed with one or more …

Purpose The stability of sildenafil in combination with heparin and dopamine was evaluated.
Methods A stability-indicating high-performance liquid chromatography method with …

First derivative and ratio derivative UV spectrophotometric methods were developed and
validated for determination of sildenafil in some adulterated tablet preparations. Sildenafil is …