Background Type 1 diabetes mellitus (T1DM) is an autoimmune disorder characterized by T
cell-mediated self-destruction of insulin-secreting islet β cells. Management of T1DM is …

Exosomes are nanosized extracellular vesicles (EVs) that show great promise in tissue
regeneration and injury repair as mesenchymal stem cell (MSC). MSC has been shown to …

The stem cells, owing to their special characteristics like self‐renewal, multiplication,
homing, immunomodulation, anti‐inflammatory, and dedifferentiation are considered to carry …

Mesenchymal stem cells (MSCs) are adult stem cells (ASCs) known for repairing damaged
cells, exerting anti‐inflammatory responses and producing immunoregulatory effects that …

Mesenchymal stem cells (MSCs) being available in numerous adult tissues and foetal
membranes have been harvested from almost all these sources in dog. Due to the presence …

Suicide gene therapy is a promising strategy for the potential treatment of hepatocellular
carcinoma (HCC). However, the lack of high transduction efficiency and targeted vectors in …

Diabetes mellitus is a chronic disease of carbohydrate metabolism characterized by
uncontrolled hyperglycemia due to the body's impaired ability to produce or respond to …

We report the restoration of euglycaemia in chemically induced diabetic C57BL/6 mice and
spontaneously diabetic Non Obese Diabetic (NOD) mice by intravenous systemic …

Abstract Type 1 diabetes (T1D) is one of the most prevalent early-onset autoimmune
diseases, and numerous treatment regimens have been developed over the years with a …

I had an opportunity to invite Sir Roy as the Joseph E. Murray, MD, Visiting Professor to our
institution in 2008. What a joy it had been to not only see the meeting of 2 giants in …