BACKGROUND Neurons are polarized cells with extreme geometries. Multiple dendrites
and one axon generally emerge from a single cell body and establish synaptic contacts with …

Highlights•Regulation of non-centrosomal microtubule organization in neurons.•Role of
resilient acetylated microtubules in mechanosensation.•Patterning microtubule tracks to …

Cortical projection neurons polarize and form an axon while migrating radially. Even though
these dynamic processes are closely interwoven, they are regulated separately—the …

Acetylation is a well-studied post-translational modification (PTM) of tubulin. Acetylated
tubulin is present in the centrioles, primary cilia, and flagella, which contain long-lived stable …

Microtubules (MTs) are an essential component of the neuronal cytoskeleton; they are
involved in various aspects of neuron development, maintenance, and functions including …

Microtubules are dynamic polymers consisting of αβ-tubulin heterodimers. The initial
polymerization process, called microtubule nucleation, occurs spontaneously via αβ-tubulin …

The manchette is a crucial transient structure involved in sperm development, with its
composition and regulation still not fully understood. This study focused on investigating the …

Microtubules (MTs) are highly dynamic polymers essential for a wide range of cellular
physiologies, such as acting as directional railways for intracellular transport and position …

Axon growth enables the rapid wiring of the central nervous system. Understanding this
process is a prerequisite to retriggering it under pathological conditions, such as a spinal …

Axons are the slender, cable-like, up to meter-long projections of neurons that electrically
wire our brains and bodies. In spite of their challenging morphology, they usually need to be …