Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

The neurovisceral integration (NVI) model was originally proposed to account for observed
relationships between peripheral physiology, cognitive performance, and emotional/physical …

Senescence is a leading cause of mortality, disability, and non‐communicable chronic
diseases in older adults. Mounting evidence indicates that the presence of cardiovascular …

There is considerable utility in the use of transcranial Doppler ultrasound (TCD) to assess
cerebrovascular function. The brain is unique in its high energy and oxygen demand but …

Cerebral autoregulation (CA) is integral to the delicate process of maintaining stable
cerebral perfusion and brain tissue oxygenation against changes in arterial blood pressure …

Components of the neurovascular unit (NVU) establish dynamic crosstalk that regulates
cerebral blood flow and maintain brain homeostasis. Here, we describe accumulating …

Optimizing cerebral perfusion is key to rescuing salvageable ischemic brain tissue. Despite
being an important determinant of cerebral perfusion, there are no effective guidelines for …

Sex is known to affect the prevalence of conditions such as stroke. However, effects of sex
on cerebral blood flow regulation are still not well understood. Critical to this understanding …

We assessed the convergent validity of commonly applied metrics of cerebral autoregulation
(CA) to determine the extent to which the metrics can be used interchangeably. To examine …

The cerebrovasculature dilates or constricts in response to acute blood pressure changes to
stabilize cerebral blood flow across a range of blood pressures. It is unclear, however …