Roles of intestinal Parabacteroides in human health and diseases

Y Cui, L Zhang, X Wang, Y Yi, Y Shan… - FEMS microbiology …, 2022 - academic.oup.com
The stability of gut microbiota is essential for the host's health. Parabacteroides spp., core
members of the human gut microbiota, have an average abundance of 1.27% in humans of …

Curcumin and colorectal cancer: An update and current perspective on this natural medicine

W Weng, A Goel - Seminars in cancer biology, 2022 - Elsevier
Colorectal cancer (CRC) is one of most common malignancies worldwide and its incidence
is still growing. In spite of recent advances in targeted therapies, their clinical efficacy has …

Immune system, microbiota, and microbial metabolites: the unresolved triad in colorectal cancer microenvironment

M Hanus, D Parada-Venegas, G Landskron… - Frontiers in …, 2021 - frontiersin.org
Colorectal cancer (CRC) is one of the most common cancers worldwide. As with other
cancers, CRC is a multifactorial disease due to the combined effect of genetic and …

Microsatellite instability in colorectal cancers: carcinogenesis, neo-antigens, immuno-resistance and emerging therapies

V Randrian, C Evrard, D Tougeron - Cancers, 2021 - mdpi.com
Simple Summary A deficient mismatch repair system (dMMR) results in microsatellite
instability (MSI). The MSI status of a tumor predicts the response to immune checkpoint …

Colon tumors in enterotoxigenic Bacteroides fragilis (ETBF)-colonized mice do not display a unique mutational signature but instead possess host-dependent …

J Allen, A Rosendahl Huber… - Microbiology …, 2022 - Am Soc Microbiol
Enterotoxigenic Bacteroides fragilis (ETBF) is consistently found at higher frequency in
individuals with sporadic and hereditary colorectal cancer (CRC) and induces tumorigenesis …

The role of the microbiome in ovarian cancer: mechanistic insights into oncobiosis and to bacterial metabolite signaling

A Sipos, G Ujlaki, E Mikó, E Maka, J Szabó, K Uray… - Molecular …, 2021 - Springer
Ovarian cancer is characterized by dysbiosis, referred to as oncobiosis in neoplastic
diseases. In ovarian cancer, oncobiosis was identified in numerous compartments, including …

The role of the microbiome on the pathogenesis and treatment of colorectal cancer

I Yu, R Wu, Y Tokumaru, KP Terracina, K Takabe - Cancers, 2022 - mdpi.com
Simple Summary The gut microbiome has recently become a hot topic for researchers
looking to understand colorectal cancer carcinogenesis and progression. Understanding the …

The microbiome and gynecologic cancer: current evidence and future opportunities

LM Chambers, P Bussies, R Vargas, E Esakov… - Current oncology …, 2021 - Springer
Abstract Purpose of Review We review the emerging evidence regarding the relationship
between the microbiota of the gastrointestinal and female reproductive tracts and …

[HTML][HTML] High soluble fiber promotes colorectal tumorigenesis through modulating gut microbiota and metabolites in mice

J Yang, H Wei, Y Lin, ESH Chu, Y Zhou, H Gou, S Guo… - Gastroenterology, 2024 - Elsevier
Background & Aims Dietary fibers are mainly fermented by the gut microbiota, but their roles
in colorectal cancer (CRC) are largely unclear. Here, we investigated the associations of …

Spice-derived bioactive compounds confer colorectal cancer prevention via modulation of gut microbiota

M Dacrema, A Ali, H Ullah, A Khan, A Di Minno, J Xiao… - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer (CRC) is a highly prevalent form of cancer, and
represents a serious, global, health threat. Available therapeutic approaches have failed to …