The increase in fracture rates and/or problems associated with missing bones due to
accidents or various pathologies generates socio-health problems with a very high impact …

At present, approximately 80% of the currently approved recombinant therapeutic proteins
are produced by Chinese hamster ovary cells. However, considering that the human …

Introduction: Cell therapy and tissue engineering has recently emerged as a new option for
short bowel syndrome (SBS) treatment, generating tissue engineered small intestine (TESI) …

Viral vectors for gene therapy, such as recombinant adeno‐associated viruses, are
produced in human embryonic kidney (HEK) 293 cells. However, the presence of the SV40 …

Background. The pathogenesis of Legg–Calve–Perthes disease (LCPD), a juvenile form of
avascular necrosis of the femoral head (ANFH), is not fully understood. Objectives. The …

Background R-spondins, including R-spondin 1 (RSPO1), are a family of Wnt ligands that
help to activate the canonical Wnt/β-catenin pathway, which is critical for intestinal epithelial …

目的· 探讨ⅡA 组磷脂酶A2 (phospholipase A2 group ⅡA, PLA2G2A) 在肾乳头状细胞癌(
kidney renal papillary cell carcinoma, KIRP) 中的表达及临床意义, 为寻找KIRP …

Epithelial organoid monoculture is a powerful tool to model stem cell dynamics in vitro.
However, extensive efforts have recently revealed various niche players and their significant …

Cystic Fibrosis (CF) is the most common, severe, autosomal recessive disease in the
Caucasian population, and is caused by mutations in the cystic fibrosis transmembrane …

Objective· To investigate the expression and clinical significance of phospholipase A2
Group ⅡA (PLA2G2A) in kidney renal papillary cell carcinoma (KIRP), and provide new …