Lung cancer is a complex thoracic malignancy developing consequential to aberrations in a
myriad of molecular and biomolecular signaling pathways. It is one of the most lethal forms …

The rapid growth of oral cancer is a significant concern, especially in developing countries
due to the advanced lifestyle and 5-year survival despite advanced multimodality of cancer …

Aim: We aimed to explore the roles of circular RNAs (circRNAs) in extracellular vesicles
(EVs) isolated from serum of patients with endometrial cancer. Materials & methods: EVs …

Esophageal squamous cell carcinoma (ESCC) is among the top ten most frequent
malignancies worldwide. In this study, our objective was to identify potential biomarkers for …

Background Platinum-based chemotherapy improves survival among patients with non-
small cell lung cancer (NSCLC), but the efficiency is limited due to resistance. In this study …

Cofilin 1 (CFL1) is a cytoskeletal protein and overexpression of the protein has been
associated with aggressiveness in certain types of malignancies. The aim of the present …

Cofilin phospho-regulation is important for actin filament turnover and is implicated in
cancer. Phosphorylation of cofilin is mediated by LIM kinases (LIMKs) and …

P-Rex1 (PIP3-dependent Rac exchanger 1, PREX1) is a Dbl-type guanine-nucleotide
exchange factor (GEF) that activates Rac-like small G proteins (small GTPases). P-Rex1 was …

Several evidences indicate that melanoma, one of the deadliest types of cancer, presents
the ability to transiently shift its phenotype under treatment or microenvironmental pressure …

Castration-resistant prostate cancer (CRPC) is a common form of prostate cancer in which
docetaxel-based chemotherapy is used as the first line. The present study is devoted to the …