Saponins are a structurally diverse class of compounds occurring in many plant species,
which are characterized by a skeleton derived of the 30-carbon precursor oxidosqualene to …

Triterpenes are naturally occurring derivatives biosynthesized following the isoprene rule of
Ruzicka. The triterpenes have been reported to possess a wide range of therapeutic …

The triterpenoids are a large group of natural products derived from C30 precursors. Nearly
200 different triterpene skeletons are known from natural sources or enzymatic reactions that …

Plants in the genus Tripterygium, such as Tripterygium wilfordii Hook. f., have a long history
of use in traditional Chinese medicine. In recent years there has been considerable interest …

Celastrol, a quinone‐methide triterpenoid, was extracted from Tripterygium wilfordii Hook. F.
in 1936 for the first time. Almost 70 years later, it is considered one of the molecules most …

Celastrol is a promising bioactive compound isolated from Tripterygium wilfordii and has
been shown to possess many encouraging preclinical applications. However, the celastrol …

Considering that exogenously applied methyl jasmonate can enhance secondary metabolite
production in a variety of plant species and that 2, 3-oxidosqualene is a common precursor …

A complexity of pathway expression in yeast compared to prokaryotes is the need for
separate promoters and terminators for each gene expressed. Single transcript expression …

Ethnopharmacological relevance Medicinal plants play a major role in many communities
across the world, in the treatment and prevention of disease and the promotion of general …

Pristimerin has been shown to be cytotoxic to several cancer cell lines. In the present work,
the cytotoxicity of pristimerin was evaluated in human tumor cell lines and in human …