Abstract Dengue, Japanese encephalitis, West Nile and yellow fever belong to the Flavivirus
genus, which is a member of the Flaviviridae family. They are human pathogens that cause …

Recent work has identified three distinct classes of viral membrane fusion proteins based on
structural criteria. In addition, there are at least four distinct mechanisms by which viral fusion …

Chikungunya virus (CHIKV) is an emerging mosquito-borne alphavirus that has caused
widespread outbreaks of debilitating human disease in the past five years. CHIKV invasion …

Viruses have evolved to enter cells from all three domains of life—Bacteria, Archaea and
Eukaryotes. Of more than 3,600 known viruses, hundreds can infect human cells and most of …

Alphaviruses are small, spherical, enveloped, positive-sense ssRNA viruses responsible for
a considerable number of human and animal diseases. Alphavirus members include …

Mature, infectious HIV‐1 particles contain a characteristic cone‐shaped core that encases
the viral RNA and replication proteins. The architectures of mature virions and isolated cores …

Abstract Structure–function studies have defined two classes of viral membrane-fusion
proteins that have radically different architectures but adopt a similar overall'hairpin' …

Genome replication and assembly of viruses often takes place in specific intracellular
compartments where viral components concentrate, thereby increasing the efficiency of the …

Improved technology for reconstructing cryo-electron microscopy (cryo-EM) images has now
made it possible to determine secondary structural features of membrane proteins in …

Semliki Forest virus (SFV) has been extensively studied as a model for analyzing entry of
enveloped viruses into target cells. Here we describe the trace of the polypeptide chain of …