Real‐time monitoring and control of the load phase of a protein A capture step

M Rüdt, N Brestrich, L Rolinger… - Biotechnology and …, 2017 - Wiley Online Library
The load phase in preparative Protein A capture steps is commonly not controlled in real‐
time. The load volume is generally based on an offline quantification of the monoclonal …

[PDF][PDF] Smart PAT concepts for the downstream process of biologics

LM Rolinger - core.ac.uk
The rapidly increasing number of originator biopharmaceuticals and their biosimilars on the
List of Essential Medicine (EML), published by the World Health Organization (WHO) …

[PDF][PDF] Development of process analytical technologies for chromatography based protein purification

N Brestrich - 2016 - scholar.archive.org
Zusammenfassung Therapeutische Proteine, wie zum Beispiel monoklonale Antikörper,
Insulin oder menschliches Wachstumshormon, stellen derzeit einen der am schnellsten …

[引用][C] Spectroscopy as process analytical technology for preparative protein purification

M Rüdt - 2019 - Dissertation, Karlsruhe, Karlsruher …