Currently, over five million Americans suffer with Alzheimer's disease (AD). In the absence of
a cure, this number could increase to 13.8 million by 2050. A critical goal of biomedical …

Spurred by availability of automatic segmentation software, in vivo MRI investigations of
human hippocampal subfield volumes have proliferated in the recent years. However, a …

Background The hippocampus and hippocampal subfields have been found to be diversely
affected in Alzheimer's Disease (AD) and early stages of Alzheimer's disease by …

Novel neuroimaging techniques that can sensitivity characterize healthy brain aging and
detect subtle neuropathologies have enormous potential to assist in the early detection of …

Like neocortical structures, the archicortical hippocampus differs in its folding patterns
across individuals. Here, we present an automated and robust BIDS-App, HippUnfold, for …

There is evidence for a hippocampal long axis anterior–posterior (AP) differentiation in
memory processing, which may have implications for the changes in episodic memory …

Introduction Unsupervised digital cognitive testing is an appealing means to capture subtle
cognitive decline in preclinical Alzheimer's disease (AD). Here, we describe development …

The hippocampus is a brain region critical for learning and memory, and is also implicated in
several neuropsychiatric disorders that show sex differences in prevalence, symptom …

With the rapidly growing population of older adults, an improved understanding of brain and
cognitive aging is critical, given the impacts on health, independence, and quality of life. To …

Age-related episodic memory decline is characterized by striking heterogeneity across
individuals. Hippocampal pattern completion is a fundamental process supporting episodic …