Pathology and genetics of hereditary colorectal cancer

H Ma, LAA Brosens, GJA Offerhaus, FM Giardiello… - Pathology, 2018 - Elsevier
Colorectal cancer (CRC) accounts for over 8% of all deaths annually worldwide. Between 2
and 5% of all CRCs occur due to inherited syndromes, including Lynch syndrome, familial …

[HTML][HTML] Precancerous lesions of the stomach, gastric cancer and hereditary gastric cancer syndromes

I Gullo, F Grillo, L Mastracci, A Vanoli, F Carneiro… - Pathologica, 2020 - ncbi.nlm.nih.gov
Gastric cancer accounts for about 6% of cancers worldwide, being the fifth most frequently
diagnosed malignancy and the third leading cause of cancer related death. Gastric …

[HTML][HTML] Management of familial adenomatous polyposis and MUTYH-associated polyposis; new insights

AS Aelvoet, F Buttitta, L Ricciardiello… - Best Practice & Research …, 2022 - Elsevier
Familial adenomatous polyposis (FAP) and MUTYH-associated polyposis (MAP) are rare
inherited polyposis syndromes with a high colorectal cancer (CRC) risk. Therefore, frequent …

Familial and hereditary gastric cancer, an overview

F Carneiro - Best Practice & Research Clinical Gastroenterology, 2022 - Elsevier
There are three major hereditable syndromes that affect primarily the stomach: hereditary
diffuse gastric cancer (HDGC), gastric adenocarcinoma and proximal polyposis of the …

Gastric polyp detection in gastroscopic images using deep neural network

C Cao, R Wang, Y Yu, H Zhang, Y Yu, C Sun - PloS one, 2021 - journals.plos.org
This paper presents the research results of detecting gastric polyps with deep learning
object detection method in gastroscopic images. Gastric polyps have various sizes. The …

Recent advances in the pathology of heritable gastric cancer syndromes

I Gullo, RS van der Post, F Carneiro - Histopathology, 2021 - Wiley Online Library
Despite the relative rarity of hereditary gastric cancer syndromes, the prompt recognition of
their specific clinical features and histopathological characteristics is pivotal in offering …

[HTML][HTML] In Silico Deciphering of the Potential Impact of Variants of Uncertain Significance in Hereditary Colorectal Cancer Syndromes

C Fasano, M Lepore Signorile, K De Marco, G Forte… - Cells, 2024 - mdpi.com
Colorectal cancer (CRC) ranks third in terms of cancer incidence worldwide and is
responsible for 8% of all deaths globally. Approximately 10% of CRC cases are caused by …

[HTML][HTML] Novel classification of gastric polyps: The good, the bad and the ugly

D Costa, D Ramai, A Tringali - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Gastric polyps (GPs) are increasingly common. On upper endoscopy, they should be
examined with white light and occasionally chromoendoscopy, and their morphology …

Molecular and pathological features of gastric cancer in Lynch syndrome and familial adenomatous polyposis

M Fornasarig, R Magris, V De Re, E Bidoli… - International Journal of …, 2018 - mdpi.com
Lynch syndrome (LS) and familial adenomatous polyposis (FAP) are autosomal dominant
hereditary diseases caused by germline mutations leading to the development of colorectal …

Hereditary gastrointestinal carcinomas and their precursors: An algorithm for genetic testing

CPE Spoto, I Gullo, F Carneiro, EA Montgomery… - Seminars in diagnostic …, 2018 - Elsevier
Recognition of hereditary forms of gastrointestinal cancer is of great importance for patients
and their families and pathologists play a crucial role in this. This review recapitulates the …