The cloning of the vanilloid receptor 1 opened a floodgate for discoveries regarding the
function of this complex molecule. It has been found that, in addition to heat, protons and …

TRPV1, the archetypal member of the vanilloid TRP family, was initially identified as the
receptor for capsaicin, the pungent ingredient in hot chili peppers. The receptor has a …

Wine Tasting: A Professional Handbook, Fourth Edition presents the latest information
behind tasting, including insights on physiological, psychological and physicochemical …

INTRODUCTION: The success rate of inferior alveolar nerve block (IANB) decreases in
patients with irreversible pulpitis. It was hypothesized that supplemental infiltration of …

Recent work has addressed the role of vanilloid receptor type 1 (VR1) in pain perception.
VR1 activity is regulated both directly and indirectly by endogenous factors. For example …

Skin temperature is sensed by peripheral thermoreceptors. Using the neuronal soma in
primary culture as a model of the receptor terminal, we have investigated the mechanisms of …

OBJECTIVE: Conventional inferior alveolar nerve block (IANB) has a poor success rate in
inflamed pulps. Three alternative techniques of providing anesthesia to mandibular molars …

The transient receptor potential channel of melastatin type 8 (TRPM8), which is gated by low
(< 25° C) temperature and chemical compounds, is regulated by protein kinase C-mediated …

Pain is an unpleasant sensation experienced when tissues are damaged. Thus, pain
sensation in some way protects body from imminent threat or injury. Peripheral sensory …

INTRODUCTION: The inferior alveolar nerve block (IANB) has a poor success rate in
patients with irreversible pulpitis. The purpose of this study was to evaluate the effect of …