[HTML][HTML] The pathogenesis of sepsis and potential therapeutic targets

M Huang, S Cai, J Su - International journal of molecular sciences, 2019 - mdpi.com
Sepsis is defined as “a life-threatening organ dysfunction caused by a host's dysfunctional
response to infection”. Although the treatment of sepsis has developed rapidly in the past …

Diagnosis of neonatal sepsis: the past, present and future

IH Celik, M Hanna, FE Canpolat, M Pammi - Pediatric research, 2022 - nature.com
Sepsis remains a significant cause of neonatal mortality and morbidity, especially in low-and
middle-income countries. Neonatal sepsis presents with nonspecific signs and symptoms …

Biomarkers for diagnosis of neonatal sepsis: a literature review

D Sharma, N Farahbakhsh, S Shastri… - The Journal of Maternal …, 2018 - Taylor & Francis
Sepsis is an important cause of mortality and morbidity in neonatal populations. There has
been constant search of an ideal sepsis biomarker that have high sensitivity, specificity …

[PDF][PDF] Neonatal sepsis

IO Odabasi, A Bulbul - Şişli Etfal Hastanesi Tip Bülteni, 2020 - jag.journalagent.com
Neonatal sepsis is associated with severe morbidity and mortality in the neonatal period.
Clinical manifestations range from subclinical infection to severe local or systemic infection …

Translational research and biomarkers in neonatal sepsis

JR Delanghe, MM Speeckaert - Clinica chimica acta, 2015 - Elsevier
As neonatal sepsis is a severe condition, there is a call for reliable biomarkers to
differentiate between infected and noninfected newborns. Although blood culture has been …

[HTML][HTML] Biomarkers of neonatal sepsis: where we are and where we are going

G Boscarino, R Migliorino, G Carbone, G Davino… - Antibiotics, 2023 - mdpi.com
Neonatal sepsis is a bacterial bloodstream infection leading to severe clinical manifestations
frequently associated with death or irreversible long-term deficits. Antibiotics are the drug of …

Advancement in biomarker based effective diagnosis of neonatal sepsis

N Gopal, N Chauhan, U Jain, SK Dass… - Artificial Cells …, 2023 - Taylor & Francis
Neonatal sepsis is considered as alarming medical emergency and becomes the common
global reason of neonatal mortality. Non-specific symptoms and limitations of conventional …

Detection of infection and sepsis in burns

MJM Torres, JM Peterson, SE Wolf - Surgical infections, 2021 - liebertpub.com
Background: Infection is the most frequent complication after severe burns and has a
propensity to progress into sepsis then septic shock and multiple organ dysfunction …

[HTML][HTML] Cytokine dysregulation persists in childhood post neonatal encephalopathy

Z Zareen, T Strickland, VM Eneaney, LA Kelly… - BMC neurology, 2020 - Springer
Background Cytokines are possible mediators of neuroinflammation and associated with
adverse outcome in neonatal encephalopathy (NE). Our aim was to explore cytokine …

[HTML][HTML] Biomarkers of neonatal sepsis: From being mere numbers to becoming guiding diagnostics

SS Gude, NC Peddi, S Vuppalapati, SV Gopal… - Cureus, 2022 - ncbi.nlm.nih.gov
Neonatal sepsis is a common cause of neonatal morbidity and mortality. The diagnosis of
newborn sepsis is still difficult. Different early objective diagnostic tests or specific signs and …