Sialic acid O-acetylation: From biosynthesis to roles in health and disease
EA Visser, SJ Moons, SBPE Timmermans… - Journal of Biological …, 2021 - ASBMB
Sialic acids are nine-carbon sugars that frequently cap glycans at the cell surface in cells of
vertebrates as well as cells of certain types of invertebrates and bacteria. The nine-carbon …
vertebrates as well as cells of certain types of invertebrates and bacteria. The nine-carbon …
Glycan-mediated molecular interactions in bacterial pathogenesis
Glycans are expressed on the surface of nearly all host and bacterial cells. Not surprisingly,
glycan-mediated molecular interactions play a vital role in bacterial pathogenesis and host …
glycan-mediated molecular interactions play a vital role in bacterial pathogenesis and host …
Sialic acids as receptors for pathogens
P Burzyńska, ŁF Sobala, K Mikołajczyk, M Jodłowska… - Biomolecules, 2021 - mdpi.com
Carbohydrates have long been known to mediate intracellular interactions, whether within
one organism or between different organisms. Sialic acids (Sias) are carbohydrates that …
one organism or between different organisms. Sialic acids (Sias) are carbohydrates that …
How bacteria utilize sialic acid during interactions with the host: snip, snatch, dispatch, match and attach
N-glycolylneuraminic acid (Neu5Gc), and its precursor N-acetylneuraminic acid (Neu5Ac),
commonly referred to as sialic acids, are two of the most common glycans found in …
commonly referred to as sialic acids, are two of the most common glycans found in …
Synthetic O-acetylated sialosides facilitate functional receptor identification for human respiratory viruses
The transmission of viruses from animal reservoirs to humans poses major threats to public
health. Preparedness for future zoonotic outbreaks requires a fundamental understanding of …
health. Preparedness for future zoonotic outbreaks requires a fundamental understanding of …
Ganglioside binding domains in proteins: Physiological and pathological mechanisms
Gangliosides are anionic lipids that form condensed membrane clusters (lipid rafts) and
exert major regulatory functions on a wide range of proteins. In this review, we propose a …
exert major regulatory functions on a wide range of proteins. In this review, we propose a …
Sialic acid diversity in the human gut: molecular impacts and tools for future discovery
Sialic acids are a family of structurally related sugars that are prevalent in mucosal surfaces,
including the human intestine. In the gut, sialic acids have diverse biological roles at the …
including the human intestine. In the gut, sialic acids have diverse biological roles at the …
Diversity of sialic acids and sialoglycoproteins in gametes and at fertilization
I Fliniaux, G Marchand, C Molinaro… - Frontiers in Cell and …, 2022 - frontiersin.org
Sialic acids are a family of 9-carbon monosaccharides with particular physicochemical
properties. They modulate the biological functions of the molecules that carry them and are …
properties. They modulate the biological functions of the molecules that carry them and are …
Salmonella typhoid toxin PltB subunit and its non-typhoidal Salmonella ortholog confer differential host adaptation and virulence
Typhoidal and non-typhoidal Salmonelleae (NTS) cause typhoid fever and gastroenteritis,
respectively, in humans. Salmonella typhoid toxin contributes to typhoid disease …
respectively, in humans. Salmonella typhoid toxin contributes to typhoid disease …
Application of the Nicoya OpenSPR to Studies of Biomolecular Binding: A Review of the Literature from 2016 to 2022
EK Hanson, RJ Whelan - Sensors, 2023 - mdpi.com
The Nicoya OpenSPR is a benchtop surface plasmon resonance (SPR) instrument. As with
other optical biosensor instruments, it is suitable for the label-free interaction analysis of a …
other optical biosensor instruments, it is suitable for the label-free interaction analysis of a …