Recent advances in the synthesis of trifluoromethyl-containing heterocyclic compounds via trifluoromethyl building blocks

Y Liu, Q Tian, J Ge, X Wu, Z Li, G Cheng - Organic & Biomolecular …, 2024 - pubs.rsc.org
Trifluoromethylated heterocyclic compounds have played an increasingly significant role in
pharmaceuticals, agrochemicals, and materials. This is because the introduction of …

Transition‐Metal‐Catalyzed Reactions Involving Trifluoro Diazo Compounds and Their Surrogates

Y Wang, C Zhang, S Li, L Liu, X Feng… - European Journal of …, 2024 - Wiley Online Library
Fluorinated organic compounds represent an important and growing family of active
ingredients in various fields, including material science, pharmaceutical chemistry and …

The [3+ 2] annulation of in situ formed trifluorodiazoethane with 4-nitroisoxazoles: access to trifluoromethylpyrazolo [3, 4-d] isoxazoles

H Wang, LQ Meng, W Niu, WQ Yang, Y Ou… - Chemical …, 2024 - pubs.rsc.org
A general and practical K2CO3-promoted [3+ 2] annulation between trifluoroacetaldehyde N-
triftosylhydrazone (TFHZ-Tfs) and 4-nitroisoxazoles has been developed to access …

In situ generated CF 3 CHN 2 with 3-ylideneoxindoles to access CF 3-containing pyrazolo [1, 5-c] quinazolines derivatives

MC Hu, HT Zhou, YC Fang, LR Zhang, BD Cui… - RSC …, 2024 - pubs.rsc.org
Toward a selective and facile method for the synthesis of CF3-containing pyrazolo [1, 5-c]
quinazolines, we developed a [3+ 2] cycloaddition/1, 3-H shift/rearrangement …

CsF-mediated reaction of diazo compounds with 3-nitroindoles: access to cyano-and phosphonylpyrazolo [4, 3-b] indoles

S Kumar, AK Gupta, NK Vaishanv, R Kant… - New Journal of …, 2024 - pubs.rsc.org
A CsF-promoted synthesis of cyanopyrazolo [4, 3-b] indoles via a [3+ 2] cycloaddition
reaction of diazoacetonitrile with N-substituted 3-nitroindoles and subsequent elimination of …