TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

CB Rodell, SP Arlauckas, MF Cuccarese… - Nature biomedical …, 2018 - nature.com
Tumour-associated macrophages are abundant in many cancers, and often display an
immune-suppressive M2-like phenotype that fosters tumour growth and promotes resistance …

A microrobotic system guided by photoacoustic computed tomography for targeted navigation in intestines in vivo

Z Wu, L Li, Y Yang, P Hu, Y Li, SY Yang, LV Wang… - Science robotics, 2019 - science.org
Recently, tremendous progress in synthetic micro/nanomotors in diverse environment has
been made for potential biomedical applications. However, existing micro/nanomotor …

Multiscale photoacoustic tomography using reversibly switchable bacterial phytochrome as a near-infrared photochromic probe

J Yao, AA Kaberniuk, L Li, DM Shcherbakova… - Nature …, 2016 - nature.com
Photoacoustic tomography (PAT) of genetically encoded probes allows for imaging of
targeted biological processes deep in tissues with high spatial resolution; however, high …

Optical focusing deep inside dynamic scattering media with near-infrared time-reversed ultrasonically encoded (TRUE) light

Y Liu, P Lai, C Ma, X Xu, AA Grabar, LV Wang - Nature communications, 2015 - nature.com
Focusing light deep inside living tissue has not been achieved despite its promise to play a
central role in biomedical imaging, optical manipulation and therapy. To address this …

Reliable and remote monitoring of absolute temperature during liver inflammation via luminescence‐lifetime‐based nanothermometry

Y Shen, J Lifante, I Zabala‐Gutierrez… - Advanced …, 2022 - Wiley Online Library
Temperature of tissues and organs is one of the first parameters affected by physiological
and pathological processes, such as metabolic activity, acute trauma, or infection‐induced …

Focusing light inside dynamic scattering media with millisecond digital optical phase conjugation

Y Liu, C Ma, Y Shen, J Shi, LV Wang - Optica, 2017 - opg.optica.org
Wavefront shaping based on digital optical phase conjugation (DOPC) focuses light through
or inside scattering media, but the low speed of DOPC prevents it from being applied to …

In vivo stiffness measurement of epidermis, dermis, and hypodermis using broadband Rayleigh-wave optical coherence elastography

X Feng, GY Li, A Ramier, AM Eltony, SH Yun - Acta Biomaterialia, 2022 - Elsevier
Traveling-wave optical coherence elastography (OCE) is a promising technique to measure
the stiffness of biological tissues. While OCE has been applied to relatively homogeneous …

Implantable and Biodegradable Poly(l‐lactic acid) Fibers for Optical Neural Interfaces

R Fu, W Luo, R Nazempour, D Tan… - Advanced Optical …, 2018 - Wiley Online Library
Advanced optical fibers and photonic structures play important roles in neuroscience
research, along with recent progresses of genetically encoded optical actuators and …

Non‐invasive detection, precise localization, and perioperative navigation of in vivo deep lesions using transmission Raman spectroscopy

Z Wu, B Deng, Y Zhou, H Xie, Y Zhang, L Lin… - Advanced …, 2023 - Wiley Online Library
Non‐invasive detection and precise localization of deep lesions have attracted significant
attention for both fundamental and clinical studies. Optical modality techniques are …

Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo

L Li, AA Shemetov, M Baloban, P Hu, L Zhu… - Nature …, 2018 - nature.com
Photoacoustic (PA) computed tomography (PACT) benefits from genetically encoded probes
with photochromic behavior, which dramatically increase detection sensitivity and specificity …