The plasminogen system has been implicated in clot lysis, wound healing, tissue
regeneration, cancer and many other processes that affect health and disease. The …

Despite the existence of extensive clinical research and novel therapeutic treatments,
cancer remains undefeated and the significant cause of death worldwide. Cancer is a …

Long-term effects of acute ischemia and reperfusion injury. Ischemia reperfusion (I/R) injury
plays a major role in delayed graft function and long-term changes after kidney …

Проблема цереброваскулярной патологии (ЦВП) и наиболее грозного ее проявления–
мозгового инсульта (МИ) имеет чрезвычайную медицинскую и социальную значимость …

Protein kinase CK2 has received a surge of attention in recent years due to the evidence of
its overexpression in a variety of solid tumors and multiple myelomas as well as its …

Atherogenesis refers to the development of atheromatous plaques in the inner lining of the
arteries. These atherosclerotic lesions are characterized by accumulation of monocyte …

The urokinase receptor (uPAR) was originally identified as the membrane receptor of the
serine protease urokinase (uPA), thereby implicated in the plasminogen activation cascade …

The host vasculature is believed to constitute the principal route of dissemination of
Neisseria meningitidis (Nm) throughout the body, resulting in septicaemia and meningitis in …

Structurally, protein kinase CK2 consists of two catalytic subunits (α and α′) and two
regulatory subunits (β), which play a critical role in targeting specific CK2 substrates …

purpose. The purpose of the study was to characterize signaling intermediates involved in
angiogenic responses of retinal endothelial cells (RECs) to the extracellular matrix and …