The production of recombinant proteins is one of the major successes of biotechnology.
Animal cells are required to synthesize proteins with the appropriate post-translational …

Recombinant antibodies and their derivatives are increasingly being used as therapeutic
agents. Clinical applications of antibodies often require large amounts of highly purified …

Using a replication-deficient retroviral vector based on the avian leukosis virus (ALV), we
inserted into the chicken genome a transgene encoding a secreted protein, β-lactamase …

Different systems are being studied and used to prepare recombinant proteins for
pharmaceutical use. The blood, and still more the milk, from transgenic animals appear a …

Much of our understanding of GH's action stems from animal models and the generation and
characterization of genetically altered or modified mice. Manipulation of genes in the …

Genetic-based animal biotechnology has produced new food and pharmaceutical products
and promises many more advances to benefit humankind. These exciting prospects are …

Transgenic animals are a useful in vivo experimental model for assessing the ability and
impact of foreign gene expression in a biological system. Transgenic mice are most …

Mammary epithelial cells grow and develop with the onset of sexual maturity. In addition,
lobular alveolar structures are formed during pregnancy, and quiescent differentiated cells …

Abstract The transcription factors Signal Transducer and Activator of Transcription (STAT)
5A/B mediate prolactin-induced mammary development during pregnancy. However, it is not …

Summary ― Human erythropoietin (EPO) gene and cDNA associated with the rabbit
whey acidic protein (WAP) gene promoter were used to tentatively produce the recombinant …