The impact of mucormycosis (black fungus) on SARS-CoV-2-infected patients: at a glance

MR Islam, MM Rahman, MT Ahasan, N Sarkar… - … Science and Pollution …, 2022 - Springer
The emergence of various diseases during the COVID-19 pandemic made health workers
more attentive, and one of the new pathogens is the black fungus (mucormycosis). As a …

Vaccinomics-based next-generation multi-epitope chimeric vaccine models prediction against Leishmania tropica - a hierarchical subtractive proteomics and …

S Aiman, A Ahmad, AA Khan, AM Alanazi… - Frontiers in …, 2023 - frontiersin.org
Leishmania tropica is a vector-borne parasitic protozoa that is the leading cause of
leishmaniasis throughout the global tropics and subtropics. L. tropica is a multidrug-resistant …

In-silico lead druggable compounds identification against SARS COVID-19 main protease target from in-house, chembridge and zinc databases by structure-based …

M Ghufran, M Ullah, HA Khan, S Ghufran, M Ayaz… - Bioengineering, 2023 - mdpi.com
Pharmacological strategies to lower the viral load among patients suffering from severe
diseases were researched in great detail during the SARS-CoV-2 outbreak. The viral …

Immunoinformatic-guided novel mRNA vaccine designing to elicit immunogenic responses against the endemic Monkeypox virus

S Aiman, Y Ali, A Malik, M Alkholief… - Journal of …, 2024 - Taylor & Francis
Monkeypox virus (MPXV) is an orthopoxvirus, causing zoonotic infections in humans with
smallpox-like symptoms. The WHO reported MPXV cases in May 2022 and the outbreak …

Exploring the natural products chemical space to abrogate the F3L-dsRNA interface of monkeypox virus to enhance the immune responses using molecular screening …

M Suleman, T Ahmad, K Shah, NA Albekairi… - Frontiers in …, 2024 - frontiersin.org
Amid the ongoing monkeypox outbreak, there is an urgent need for the rapid development of
effective therapeutic interventions capable of countering the immune evasion mechanisms …

Rational design of multi-epitope-based vaccine by exploring all dengue virus serotypes proteome: an immunoinformatic approach

AA Alsaiari, MA Hakami, BS Alotaibi, SS Alkhalil… - Immunologic …, 2024 - Springer
Millions of people's lives are being devastated by dengue virus (DENV), a severe tropical
and subtropical illness spread by mosquitoes and other vectors. Dengue fever may be self …

Designing of a multi-epitopes based vaccine against Haemophilius parainfluenzae and its validation through integrated computational approaches

SA Ghaffar, H Tahir, S Muhammad, M Shahid… - Frontiers in …, 2024 - frontiersin.org
Haemophilus parainfluenzae is a Gram-negative opportunist pathogen within the mucus of
the nose and mouth without significant symptoms and has an ability to cause various …

The deceptive COVID-19: lessons from common molecular diagnostics and a novel plan for the prevention of the next pandemic

DS Mouliou - Diseases, 2023 - mdpi.com
The COVID-19 pandemic took place during the years 2020–2022 and the virus, named
SARS-CoV-2, seems likely to have resulted in an endemic disease. Nevertheless …

Cross-protection induced by highly conserved human B, CD4+, and CD8+ T-cell epitopes-based vaccine against severe infection, disease, and death caused by …

S Prakash, NR Dhanushkodi, L Zayou… - Frontiers in …, 2024 - frontiersin.org
Background The coronavirus disease 2019 (COVID-19) pandemic has created one of the
largest global health crises in almost a century. Although the current rate of Severe acute …

Integrating core subtractive proteomics and reverse vaccinology for multi-epitope vaccine design against Rickettsia prowazekii endemic typhus

A Khan, MH Khanzada, K Khan, K Jalal, R Uddin - Immunologic Research, 2024 - Springer
Rickettsia prowazekii is an intracellular, obligate, gram-negative coccobacillus responsible
for epidemic typhus. Usually, the infected body louse or its excrement when rubbed into the …