Alzheimer's disease (AD) is a heterogeneous neurodegenerative disease with multifaceted neuropathological disorders. AD is characterized by intracellular accumulation of …
Alzheimer's disease is a chronic and degenerative condition that had no treatment until recently. The current therapeutic strategies reduce progression of the disease but are …
Neurological disorders represent major health concerns in terms of comorbidity and mortality worldwide. Despite a tremendous increase in our understanding of the …
Abstract Purpose of Review To provide an overview of the association between angiotensin II receptor blocker (ARB) use and cognitive outcomes. Recent Findings ARBs have …
PK Singh, ZL Chen, D Ghosh, S Strickland… - Neurobiology of …, 2020 - Elsevier
Alzheimer's disease (AD) is characterized by the presence of proteinaceous brain deposits, brain atrophy, vascular dysfunction, and chronic inflammation. Along with cerebral …
C Sharo, T Zhai, Z Huang - Pharmaceuticals, 2024 - mdpi.com
Alzheimer's disease has become a major public health issue. While extensive research has been conducted in the last few decades, few drugs have been approved by the FDA to treat …
C Petrella, MG Di Certo, C Barbato… - Current Alzheimer …, 2019 - ingentaconnect.com
Neuropeptides are small proteins broadly expressed throughout the central nervous system, which act as neurotransmitters, neuromodulators and neuroregulators. Growing evidence …
S Peineau, K Rabiant, O Pierrefiche, B Potier - Pharmacological Research, 2018 - Elsevier
Synaptic plasticity is a cellular process involved in learning and memory whose alteration in its two main forms (Long Term Depression (LTD) and Long Term Potentiation (LTP)), is …
B Lacoste, XK Tong, K Lahjouji, R Couture… - Journal of …, 2013 - Springer
Background Recent evidence suggests that the inducible kinin B 1 receptor (B 1 R) contributes to pathogenic neuroinflammation induced by amyloid-beta (Aβ) peptide. The …