Boronic acid based dynamic click chemistry: recent advances and emergent applications

S Chatterjee, EV Anslyn, A Bandyopadhyay - Chemical science, 2021 - pubs.rsc.org
Recently, reversible click reactions have found numerous applications in chemical biology,
supramolecular chemistry, and biomedical applications. Boronic acid (BA)-mediated cis-diol …

Phage display based biosensing: Recent advances and challenges

M Wang, S Pang, H Zhang, Z Yang, A Liu - TrAC Trends in Analytical …, 2024 - Elsevier
Phage display enables to screen probes such as peptide, antibody and nanobody with high
specificity and affinity to the target, providing excellent probes for various analytical or …

Lysine-targeted reversible covalent ligand discovery for proteins via phage display

M Zheng, FJ Chen, K Li, RM Reja… - Journal of the …, 2022 - ACS Publications
Binding via reversible covalent bond formation presents a novel and powerful mechanism to
enhance the potency of synthetic inhibitors for therapeutically important proteins. Work on …

Screening of bio-recognition elements by phage display and their application in the detection of foodborne pathogens

S Wu, L Sheng, X Lu, Y Ye, J Sun, J Ji, J Shao… - TrAC Trends in …, 2024 - Elsevier
Foodborne pathogens are an important cause of food safety problems. However, detection
of low number of pathogens in foods can be challenging, as the available recognition …

Phage display-derived peptides and antibodies for bacterial infectious diseases therapy and diagnosis

H Zhao, D Nie, Y Hu, Z Chen, Z Hou, M Li, X Xue - Molecules, 2023 - mdpi.com
The emergence of antibiotic-resistant-bacteria is a serious public health threat, which
prompts us to speed up the discovery of novel antibacterial agents. Phage display …

Diversification of Phage-Displayed Peptide Libraries with Noncanonical Amino Acid Mutagenesis and Chemical Modification

JT Hampton, WR Liu - Chemical reviews, 2024 - ACS Publications
Sitting on the interface between biologics and small molecules, peptides represent an
emerging class of therapeutics. Numerous techniques have been developed in the past 30 …

Boron enabled bioconjugation chemistries

M Zheng, L Kong, J Gao - Chemical Society Reviews, 2024 - pubs.rsc.org
Novel bioconjugation reactions have been heavily pursued for the past two decades. A
myriad of conjugation reactions have been developed for labeling molecules of interest in …

Bactericidal urea crown ethers target phosphatidylethanolamine membrane lipids

SR Herschede, H Gneid, T Dent, EB Jaeger… - Organic & …, 2021 - pubs.rsc.org
An increasing number of people are infected with antibiotic-resistant bacteria each year,
sometimes with fatal consequences. In this manuscript, we report a novel urea …

Structure‐Activity Relationships in Supramolecular Hosts Targeting Bacterial Phosphatidylethanolamine (PE) Lipids

EO Ojah, H Gneid, SR Herschede… - … –A European Journal, 2024 - Wiley Online Library
Abstract The World Health Organization has described the antimicrobial resistance crisis as
one of the top ten global public health threats. New antimicrobial agents that can fight …

Magnetophoretic microdevices for lipopolysaccharide removal from blood: design through advanced simulation techniques

C González Fernández - 2022 - repositorio.unican.es
Extracorporeal blood detoxification using magnetic cleansing microdevices (MCMDs) has
been understood as a promising strategy to abate infectious diseases as alternative to the …