Effective tumor treatment depends on optimizing drug penetration and accumulation in
tumor tissue while minimizing systemic toxicity. Nanomedicine has emerged as a key …

Oncolytic peptides represent promising novel candidates for anticancer treatments. In our
efforts to develop oncolytic peptides possessing both high protease stability and durable …

Pancreatic cancer is a devastating disease with a high mortality rate and a lack of effective
therapies. The challenges associated with early detection and the highly aggressive nature …

The effectiveness of chemotherapeutic agents for hepatocellular carcinoma (HCC) is
unsatisfactory because of tumor heterogeneity, multidrug resistance, and poor target …

Pancreatic cancer poses a significant challenge within the field of oncology due to its
aggressive behaviour, limited treatment choices, and unfavourable outlook. With a mere …

Messenger ribonucleic acid (mRNA)-based gene therapy has great potential for cancer
gene therapy. However, the effectiveness of mRNA in cancer therapy needs to be further …

Despite the important breakthroughs of immune checkpoint inhibitors in recent years, the
objective response rates remain limited. Here, we synthesize programmed cell death protein …

Background Messenger ribonucleic acid (mRNA)-based gene therapy has great potential in
cancer treatment. However, the application of mRNA-based cancer treatment could be …

One of the primary threats in tumor treatment revolves around the limited ability to penetrate
tumor sites, leading to reduced therapeutic effectiveness, which remains a critical concern …

Central nervous system lymphoma (CNSL) is a type of hematological tumor. Treatment of
CNSL is difficult due to the existence of the blood–brain barrier (BBB). Here, we used …