Carotenoids are important precursors of a wide range of apocarotenoids with their functions
including: hormones, pigments, retinoids, volatiles, and signals, which can be used in the …

Highlights•Microbial cell factories offer sustainable and renewable production of natural
esters.•Modular cell design enables rapid construction of optimal ester-producing strains …

Interactions between the microbiota and mammalian host are essential for defense against
infection, but the microbial-derived cues that mediate this relationship remain unclear. Here …

In 1948, the first kilograms of synthetic vitamin A (acetate) were produced by F. Hoffmann-La
Roche, eliminating the need to extract this vital compound from natural sources; this year …

Monoterpenes, such as the cyclic terpene limonene, are valuable and important natural
products widely used in food, cosmetics, household chemicals, and pharmaceutical …

Conversion of dietary vitamin A (VA) into retinoic acid (RA) is essential for many biological
processes and thus far studied largely in mammalian cells. Using targeted metabolomics …

The demand for bio-based retinol (vitamin A) is currently increasing, however its instability
represents a major bottleneck in microbial production. Here, we developed an efficient …

The efficiency and productivity of cellular biocatalysts play a key role in the industrial
synthesis of fine and bulk chemicals. This study focuses on optimizing the synthesis of (S) …

Isoprenoids comprise the largest family of natural organic compounds with many useful
applications in the pharmaceutical, nutraceutical, and industrial fields. Rapid developments …

There are more than 4000 natural and synthetic molecules structurally and/or functionally
related to vitamin A. Retinoids are a class of these compounds that are structurally …