Imaging techniques in Alzheimer's disease: a review of applications in early diagnosis and longitudinal monitoring

WM van Oostveen, ECM de Lange - International journal of molecular …, 2021 - mdpi.com
Background. Alzheimer's disease (AD) is a progressive neurodegenerative disorder
affecting many individuals worldwide with no effective treatment to date. AD is characterized …

Preclinical Alzheimer's disease: definition, natural history, and diagnostic criteria

B Dubois, H Hampel, HH Feldman, P Scheltens… - Alzheimer's & …, 2016 - Elsevier
During the past decade, a conceptual shift occurred in the field of Alzheimer's disease (AD)
considering the disease as a continuum. Thanks to evolving biomarker research and …

Multimodal deep learning for Alzheimer's disease dementia assessment

S Qiu, MI Miller, PS Joshi, JC Lee, C Xue, Y Ni… - Nature …, 2022 - nature.com
Worldwide, there are nearly 10 million new cases of dementia annually, of which
Alzheimer's disease (AD) is the most common. New measures are needed to improve the …

Development and validation of an interpretable deep learning framework for Alzheimer's disease classification

S Qiu, PS Joshi, MI Miller, C Xue, X Zhou, C Karjadi… - Brain, 2020 - academic.oup.com
Alzheimer's disease is the primary cause of dementia worldwide, with an increasing
morbidity burden that may outstrip diagnosis and management capacity as the population …

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

B Dubois, HH Feldman, C Jacova, H Hampel… - The Lancet …, 2014 - thelancet.com
In the past 8 years, both the International Working Group (IWG) and the US National Institute
on Aging–Alzheimer's Association have contributed criteria for the diagnosis of Alzheimer's …

Plasma phospholipids identify antecedent memory impairment in older adults

M Mapstone, AK Cheema, MS Fiandaca, X Zhong… - Nature medicine, 2014 - nature.com
Alzheimer's disease causes a progressive dementia that currently affects over 35 million
individuals worldwide and is expected to affect 115 million by 2050 (ref. 1). There are no …

Metabolic dysregulation contributes to the progression of Alzheimer's disease

X Yan, Y Hu, B Wang, S Wang, X Zhang - Frontiers in neuroscience, 2020 - frontiersin.org
Alzheimer's disease (AD) is an incurable neurodegenerative disease. Numerous studies
have demonstrated a critical role for dysregulated glucose metabolism in its pathogenesis …

Early diagnosis of Alzheimer's disease: the role of biomarkers including advanced EEG signal analysis. Report from the IFCN-sponsored panel of experts

PM Rossini, R Di Iorio, F Vecchio, M Anfossi… - Clinical …, 2020 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative disease among the
elderly with a progressive decline in cognitive function significantly affecting quality of life …

Insulin resistance and Alzheimer's disease: bioenergetic linkages

BJ Neth, S Craft - Frontiers in aging neuroscience, 2017 - frontiersin.org
Metabolic dysfunction is a well-established feature of Alzheimer's disease (AD), evidenced
by brain glucose hypometabolism that can be observed potentially decades prior to the …

Brain fluorodeoxyglucose (FDG) PET in dementia

T Kato, Y Inui, A Nakamura, K Ito - Ageing research reviews, 2016 - Elsevier
The purpose of this article is to present a selective and concise summary of
fluorodeoxyglucose (FDG) positron emission tomography (PET) in dementia imaging. FDG …