Interferon receptor trafficking and signaling: Journey to the cross roads

N Zanin, C Viaris de Lesegno, C Lamaze… - Frontiers in …, 2021 - frontiersin.org
Like most plasma membrane proteins, type I interferon (IFN) receptor (IFNAR) traffics from
the outer surface to the inner compartments of the cell. Long considered as a passive means …

Molecular and cellular factors determining the functional pleiotropy of cytokines

A McFarlane, E Pohler, I Moraga - The FEBS Journal, 2023 - Wiley Online Library
Cytokines are soluble factors vital for mammalian physiology. Cytokines elicit highly
pleiotropic activities, characterized by their ability to induce a wide spectrum of functional …

High-speed compressed-sensing fluorescence lifetime imaging microscopy of live cells

Y Ma, Y Lee, C Best-Popescu… - Proceedings of the …, 2021 - National Acad Sciences
We present high-resolution, high-speed fluorescence lifetime imaging microscopy (FLIM) of
live cells based on a compressed sensing scheme. By leveraging the compressibility of …

Plasma membrane nanodeformations promote actin polymerisation through CIP4/CDC42 recruitment and regulate type II IFN signaling

L Benjamin, Z Natacha, Y Jinsung, C Charlotte… - bioRxiv, 2022 - biorxiv.org
In their environment, cells have to cope with mechanical stresses constantly. Among those,
nanoscale deformations of plasma membrane induced by substrate nanotopography are …