Purpose Emerging evidence suggests a detrimental prognostic association between
radiation-induced lymphopenia (RIL) and pathologic response, progression-free survival …

Radiation-induced lymphopenia (RIL) is characterized by a significant decrease in the
absolute number of lymphocytes circulating in the blood after radiotherapy. With the major …

Background: Dexamethasone (DEX) is widely adopted to reduce tumor-associated edema
in glioblastoma (GBM) patients despite its side effects. However, the benefits of using DEX in …

Despite significant advances in our knowledge regarding the genetics and molecular
biology of gliomas over the past two decades and hundreds of clinical trials, no effective …

Purpose Glioblastomas, the most common primary malignant brain tumors in adults, still
hold poor prognosis. Corticosteroids, such as dexamethasone, are usually prescribed to …

Introduction Malignant gliomas are the most common primary malignant brain tumors and
are typically treated with maximal safe surgical resection followed by chemoradiation. One of …

Dexamethasone has been commonly given to patients with a presumed new GBM in
relatively large doses (6-16 mg daily for 1-2 weeks) since the 1960s without any rigorous …

Background We examined the effect of dexamethasone prescribed in the initial 3
postoperative weeks on survival, steroid dependency, and infection in glioblastoma patients …

Glioblastoma, the most prevalent malignant primary brain tumor, presents substantial
treatment challenges because of its inherent aggressiveness and limited therapeutic …

Background Lymphopenia may lead to worse outcomes for glioblastoma patients. This study
is a secondary analysis of the CCTG CE. 6 trial evaluating the impact of chemotherapy and …