Topical products, widely used to manage skin conditions, have evolved from simple potions
to sophisticated delivery systems. Their development has been facilitated by advances in …

Water is absolutely essential for the normal functioning of the skin and especially its outer
layer, the stratum corneum (SC). Loss of water from the skin must be carefully regulated, a …

Written by experienced and internationally renowned contributors, this is the fourth edition of
what has become the standard reference for cosmetic scientists and dermatologists seeking …

Aquaporins (AQPs) are integral membrane proteins and found in all living organisms from
bacteria to human. AQPs mainly involved in the transmembrane diffusion of water as well as …

The skin is essential for terrestrial life. It is responsible for regulating water permeability and
functions as a mechanical barrier that protects against environmental insults such as …

The discovery of aquaporin water channels by Agre and coworkers answered a long-
standing biophysical question of how the majority of water crosses biological membranes …

Aquaporin-3 (AQP3) is a membrane transporter of water and glycerol expressed in plasma
membranes in the basal layer keratinocytes of epidermis in normal skin. AQP3 expression in …

Psoriasis is a complex inflammatory disease that usually heals without visible scarring.
Histological evaluation often suggests complete resolution, but reversal of genomic disease …

The decisive role of the epidermis in maintaining body homeostasis prompted studies to
evaluate the changes in epidermal structure and functionality over the lifetime. This …

Aquaporins (AQPs) are a family of membrane water channels that basically function as
regulators of intracellular and intercellular water flow. To date, thirteen AQPs, which are …