The effect of human immunodeficiency virus and cytomegalovirus infection on infant responses to vaccines: a review

O Falconer, ML Newell, CE Jones - Frontiers in immunology, 2018 - frontiersin.org
The success of prevention of mother to child transmission programs over the last two
decades has led to an increasing number of infants who are exposed to human …

Growth reconstitution following antiretroviral therapy and nutritional supplementation: systematic review and meta-analysis

CJ McGrath, L Diener, BA Richardson… - Aids, 2015 - journals.lww.com
Objective: As antiretroviral therapy (ART) expands for HIV-infected children, it is important to
determine its impact on growth. We quantified growth and its determinants following ART in …

Xpert HIV-1 point-of-care test for neonatal diagnosis of HIV in the birth testing programme of a maternity hospital: a field evaluation study

KG Technau, L Kuhn, A Coovadia, PM Murnane… - The lancet HIV, 2017 - thelancet.com
Background Point-of-care testing (POCT) among HIV-exposed infants might improve linkage
to care relative to laboratory-based testing (LABT). We evaluated HIV-1 POCT at birth in the …

Despite access to antiretrovirals for prevention and treatment, high rates of mortality persist among HIV-infected infants and young children

EJ Abrams, S Woldesenbet, JS Silva… - The Pediatric …, 2017 - journals.lww.com
Background: Outcomes of HIV-infected children before widespread use of antiretroviral
therapy (ART) for treatment and prevention of mother-to-child transmission (PMTCT) have …

Urgent versus post-stabilisation antiretroviral treatment in hospitalised HIV-infected children in Kenya (PUSH): a randomised controlled trial

IN Njuguna, LM Cranmer, VO Otieno, C Mugo… - The lancet HIV, 2018 - thelancet.com
Background Urgent antiretroviral therapy (ART) among hospitalised HIV-infected children
might accelerate recovery or worsen outcomes associated with immune reconstitution. We …

Implementation and operational research: active referral of children of HIV-positive adults reveals high prevalence of undiagnosed HIV

AD Wagner, C Mugo, IN Njuguna… - JAIDS Journal of …, 2016 - journals.lww.com
Objectives: Few routine systems exist to test older, asymptomatic children for HIV. Testing all
children in the population has high uptake but is inefficient, whereas testing only …

Long-term survival outcomes of HIV infected children receiving antiretroviral therapy: an observational study from Zambia (2003–2015)

JN Mutanga, S Mutembo, AE Ezeamama, X Song… - BMC Public …, 2019 - Springer
Abstract Background In 2017, 64% of children living with HIV in Zambia accessed
Antiretroviral Therapy (ART). Despite expanded ART coverage, there is paucity of …

Higher HIV-1 Env gp120-specific antibody-dependent cellular cytotoxicity (ADCC) activity is associated with lower levels of defective HIV-1 provirus

R Yucha, ML Litchford, CS Fish, ZA Yaffe… - Viruses, 2023 - mdpi.com
A cure for HIV-1 (HIV) remains unrealized due to a reservoir of latently infected cells that
persist during antiretroviral therapy (ART), with reservoir size associated with adverse health …

Systems Analysis and Improvement Approach to optimize the pediatric and adolescent HIV Cascade (SAIA-PEDS): a pilot study

AD Wagner, O Augusto, IN Njuguna, D Gaitho… - Implementation Science …, 2022 - Springer
Introduction Children and adolescents lag behind adults in achieving UNAIDS 95-95-95
targets for HIV testing, treatment, and viral suppression. The Systems Analysis and …

Improving early identification of HIV‐infected neonates with birth PCR testing in a large urban hospital in Johannesburg, South Africa: successes and challenges

KG Technau, L Kuhn, A Coovadia… - African Journal of …, 2017 - journals.lww.com
Methods We implemented a pilot universal birth HIV PCR testing programme at RMMCH in
order to diagnose HIV‐infected neonates as early as possible and initiate ART. At this time …