INTRODUCTION Axolotls (Ambystoma mexicanum) and other salamanders are the only
tetrapods that can regenerate whole limbs. During this complex process, changes in gene …

In order to contribute to the appropriate tissues during development, cells need to know their
position within the embryo. This positional information is conveyed by gradients of signaling …

Wound healing is a fundamental evolutionary adaptation with two possible outcomes: scar
formation or reparative regeneration. Scars participate in re-forming the barrier with the …

In many animal species with a bilateral symmetry, Hox genes are clustered either at one or
at several genomic loci. This organization has a functional relevance, as the transcriptional …

The regenerative capacity varies significantly among the animal kingdom. Successful
regeneration program in some animals results in the functional restoration of tissues and lost …

In recent years, interest in the possible molecular regulators of cell proliferation and
differentiation in a wide range of regeneration models has grown significantly, but the cell …

Neural crest cells (NCCs) are a vertebrate-specific, multipotent stem cell population that
have the ability to migrate and differentiate into various cell populations throughout the …

The axolotl is a highly regenerative organism and has been studied in laboratories for over
150 years. Despite a long‐standing fascination with regeneration in general and axolotl …

Abstract Axolotl (Ambystoma Mexicanum) has been emerging as a promising model in stem
cell and regeneration researches due to its exceptional regenerative capacity. Although it …

Abstract The Mexican axolotl (Ambystoma mexicanum) is a critically endangered species
and a fruitful amphibian model for regenerative biology. Despite growing body of research …