Several macromolecular machines collaborate to produce eukaryotic messenger RNA. RNA
polymerase II (Pol II) translocates along genes that are up to millions of base pairs in length …

The carcinoembryonic antigen (CEA) gene family belongs to the immunoglobulin supergene
family and can be divided into two main subgroups based on sequence comparisons. In …

Precisely defining the roles of specific cell types is an intriguing frontier in the study of intact
biological systems and has stimulated the rapid development of genetically encoded tools …

Motivation: We introduce gmap, a standalone program for mapping and aligning cDNA
sequences to a genome. The program maps and aligns a single sequence with minimal …

Deletions giving rise to Duchenne muscular dystrophy (DMD) and the less severe Becker
muscular dystrophy (BMD) occur in the same large gene on the short arm of the human X …

Vascular endothelial cell growth factor, a mitogen selective for vascular endothelial cells in
vitro that promotes angiogenesis in vivo, functions through distinct membrane-spanning …

A systematic analysis of the RNA splice junction sequences of eukaryotic protein coding
genes was carried out using the GENBANK databank. Nucleotide frequencies obtained for …

Summary The To//gene of Drosophila, a maternal effect gene that plays a central role in the
establishment of the embryonic dorsal-ventral pattern, has been cloned using P element …

We have isolated the Drosophila melanogaster homolog (Dint-l) of in&l, a conserved cellular
oncogene implicated in viral mammary tumorigenesis In mice. The deduced Dint-l protein …

The complete sequence of the human Duchenne muscular dystrophy (DMD) cDNA has
been determined. The 3685 encoded amino acids of the protein product, dystrophin, can be …