Oxidative stress causes various diseases, such as type II diabetes and dyslipidemia, while
antioxidants in foods may prevent a number of diseases and delay aging by exerting their …

The retinal pigment epithelium (RPE) performs a range of necessary functions within the
neural layers of the retina and helps ensure vision. The regulation of pro-oxidative and …

Na+/K+-ATPase (NKA), a large transmembrane protein, is expressed in the plasma
membrane of most eukaryotic cells. It maintains resting membrane potential, cell volume and …

Prenatal exposure to infections is a risk factor for neurodevelopmental disorders in offspring,
and alterations in mitochondrial function are discussed as a potential underlying factor …

Memantine is an FDA-approved, non-competitive NMDA-receptor antagonist that has been
shown to have mitochondrial protective effects, improve cell viability and enhance clearance …

Alzheimer's disease is the most prevalent neurodegenerative disorder and affects the lives
not only of those who are diagnosed but also of their caregivers. Despite the enormous …

Millions of individuals around the world are afflicted with Parkinson's disease (PD), a
prevalent and incapacitating neurodegenerative disorder. Dr. Reichmann, a distinguished …

Prolonged activation of microglia leads to excessive release of proinflammatory mediators,
which are detrimental to brain health. Therefore, there are significant efforts to identify …

Inflammation and resolution are highly programmed processes involving a plethora of
immune cells. Lipid mediators synthesized from arachidonic acid metabolism play a pivotal …

Abstract Although uncoupling protein 4 (UCP4) is the most abundant protein reported in the
brain, the biological function of UCP4 in cerebellum and pathological outcome of UCP4 …