The transport of specific molecules across lipid membranes is an essential function of all
living organisms. The processes are usually mediated by specific transporters. One of the …

Cells with stem‐like properties, tumorigenic potential, and treatment‐resistant phenotypes
have been identified in many human malignancies. Based on the properties they share with …

Multidrug transporter proteins are best known for their contributions to chemoresistance
through the efflux of anticancer drugs from cancer cells. However, a considerable body of …

2014-11-12 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

Recent studies have indicated that cancer stem-like cells (CSCs) exhibit a high resistance to
current therapeutic strategies, including photodynamic therapy (PDT), leading to the …

Glioblastoma multiforme (GBM) is considered the most common and aggressive tumour of
the central nervous system and is characterized for being highly chemoresistant. This …

Angiogenesis of capillary endothelial cells includes at least four sequential cellular
responses: digestion of basement membrane, migration, proliferation, and differentiation. To …

Glioblastoma (GBM) is one of the most malignant tumors with poor prognosis and outcomes.
Although smaller particle size can lead to higher blood-brain barrier (BBB)-permeability of …

The importance of DNA repair as a resistance mechanism in gliomas, the most aggressive
form of brain tumor, is a clinically relevant topic. Recent studies show that not all cells are …

The poor response of glioblastoma to current treatment protocols is a consequence of its
intrinsic drug resistance. Resistance to chemotherapy is primarily associated with …