Mesonephric-like adenocarcinoma of the uterine corpus: Genomic and immunohistochemical profiling with comprehensive clinicopathological analysis of 17 …

HH Koh, E Park, HS Kim - Biomedicines, 2023 - mdpi.com
Data on genetic and immunophenotypical characteristics of uterine mesonephric-like
adenocarcinoma (MLA) remain limited. Therefore, we aimed to investigate the …

[HTML][HTML] Ovarian Mesonephric-like Adenocarcinoma: Its Prevalence in a Japanese High-Volume Cancer Center and a Literature Review on Therapeutic Targets

A Ogawa, H Yoshida, S Kawano, N Kikkawa… - Current …, 2024 - mdpi.com
Background: Ovarian mesonephric-like adenocarcinoma (MLA) is a newly described
histological type known for its aggressive behavior. This study aims to determine the …

Mesonephric‐type adenocarcinomas of the ovary: prevalence, diagnostic reproducibility, outcome, and value of PAX2

M Köbel, EY Kang, S Lee, T Ogilvie… - The Journal of …, 2024 - Wiley Online Library
Abstract Mesonephric‐type (or‐like) adenocarcinomas (MAs) of the ovary are an uncommon
and aggressive histotype. They appear to arise through transdifferentiation from Müllerian …

Endometrial carcinosarcomas are almost exclusively of p53abn molecular subtype after exclusion of mimics

J Huvila, A Jamieson, J Pors, L Hoang… - International Journal …, 2024 - journals.lww.com
Methods Forty-one carcinosarcomas were identified from a cohort of 973 endometrial
carcinomas diagnosed in 2016. We assessed immunostaining and sequencing data and …

POLE-mutated Endometrial “Carcinosarcoma”

A De Boeck, E Nohr, S El-Hallani… - International Journal …, 2025 - journals.lww.com
The molecular subtype classification of endometrial carcinomas has conceptually changed
our approach to this disease. However, open questions remain about how to integrate …

Controversies in the Management of Mesonephric and Mesonephric-like Adenocarcinomas of the Female Genital Tract

AM Praiss, KJ Park, S Makker, J Girshman… - International Journal of …, 2025 - Elsevier
Mesonephric and mesonephric-like adenocarcinomas of the gynecologic tract are a rare
subset of gynecologic tumors that are frequently associated with the presence of somatic …

Papillary and ductal patterns of mesonephric‐like adenocarcinomas are often overlooked: a retrospective revaluation of over 1000 endometrial carcinomas

A Akbari, J Pors, A Lum, S Leung, D Cochrane… - …, 2024 - Wiley Online Library
Aims Mesonephric‐like adenocarcinoma (MLA) of the endometrium is often a diagnostic
challenge, due to its morphological resemblance to other more common Müllerian …

From morphology to methylome: epigenetic studies of Müllerian mesonephric‐like adenocarcinoma reveal similarities to cervical mesonephric adenocarcinoma

LH Lin, BE Howitt, DL Kolin - The Journal of Pathology, 2024 - Wiley Online Library
Mesonephric adenocarcinomas (MAs) and mesonephric‐like adenocarcinomas (MLAs) are
rare, aggressive neoplasms that arise in the gynecologic tract and show overlapping …

Genomic profiling of dedifferentiated endometrial carcinomas arising in the background of high‐grade carcinoma: a targeted next‐generation sequencing study

E Olkhov‐Mitsel, A Busca, C Parra‐Herran… - …, 2023 - Wiley Online Library
Aims Our understanding of dedifferentiated endometrial carcinoma (DEC), a rare and
aggressive malignancy, mainly reflects undifferentiated carcinomas (UC) arising in the …

Mesonephric adenocarcinoma of the uterine cervix with a prominent spindle cell component

Y Fan, Y He, L Sun, T Liu, Y Shen - Oncology Letters, 2024 - spandidos-publications.com
Mesonephric adenocarcinomas (MAs) with spindle cell components are rare malignant
cervical tumours. In the present study, a retrospective analysis of these tumours was …