Circular RNA translation, a path to hidden proteome
Functional proteins in the cell are translated from the messenger RNA (mRNA) molecules,
constituting less than 5% of the cellular transcriptome. The majority of the RNA molecules in …
constituting less than 5% of the cellular transcriptome. The majority of the RNA molecules in …
3′ UTR heterogeneity and cancer progression
JJ Chan, H Tabatabaeian, Y Tay - Trends in Cell Biology, 2023 - cell.com
The majority of human mRNAs generate alternative 3′ untranslated regions (UTRs)
through various processes, including RNA modifications such as RNA editing, m 6 A …
through various processes, including RNA modifications such as RNA editing, m 6 A …
m6A-Atlas: a comprehensive knowledgebase for unraveling the N6-methyladenosine (m6A) epitranscriptome
Abstract N 6-Methyladenosine (m6A) is the most prevalent RNA modification on mRNAs and
lncRNAs. It plays a pivotal role during various biological processes and disease …
lncRNAs. It plays a pivotal role during various biological processes and disease …
DirectRMDB: a database of post-transcriptional RNA modifications unveiled from direct RNA sequencing technology
With advanced technologies to map RNA modifications, our understanding of them has
been revolutionized, and they are seen to be far more widespread and important than …
been revolutionized, and they are seen to be far more widespread and important than …
[HTML][HTML] scDART-seq reveals distinct m6A signatures and mRNA methylation heterogeneity in single cells
Summary N 6-methyladenosine (m 6 A) is an abundant RNA modification that plays critical
roles in RNA regulation and cellular function. Global m 6 A profiling has revealed important …
roles in RNA regulation and cellular function. Global m 6 A profiling has revealed important …
m6A-Atlas v2.0: updated resources for unraveling the N6-methyladenosine (m6A) epitranscriptome among multiple species
Abstract N 6-Methyladenosine (m6A) is one of the most abundant internal chemical
modifications on eukaryote mRNA and is involved in numerous essential molecular …
modifications on eukaryote mRNA and is involved in numerous essential molecular …
N6-methyladenosine regulates maternal RNA maintenance in oocytes and timely RNA decay during mouse maternal-to-zygotic transition
Y Wu, X Xu, M Qi, C Chen, M Li, R Yan, X Kou… - Nature cell …, 2022 - nature.com
Abstract N 6-methyladenosine (m6A) and its regulatory components play critical roles in
various developmental processes in mammals. However, the landscape and function of …
various developmental processes in mammals. However, the landscape and function of …
CircRHBDD1 augments metabolic rewiring and restricts immunotherapy efficacy via m6A modification in hepatocellular carcinoma
J Cai, Z Chen, Y Zhang, J Wang, Z Zhang, J Wu… - Molecular Therapy …, 2022 - cell.com
Circular RNAs are a class of highly conserved RNAs with stable covalently closed circular
structures. Metabolic reprogramming of cancer cells reshapes the tumor microenvironment …
structures. Metabolic reprogramming of cancer cells reshapes the tumor microenvironment …
DENA: training an authentic neural network model using Nanopore sequencing data of Arabidopsis transcripts for detection and quantification of N6 …
Abstract Models developed using Nanopore direct RNA sequencing data from in vitro
synthetic RNA with all adenosine replaced by N 6-methyladenosine (m6A) are likely …
synthetic RNA with all adenosine replaced by N 6-methyladenosine (m6A) are likely …
m6A readers, writers, erasers, and the m6A epitranscriptome in breast cancer
Epitranscriptomic modification of RNA regulates human development, health, and disease.
The true diversity of the transcriptome in breast cancer including chemical modification of …
The true diversity of the transcriptome in breast cancer including chemical modification of …