Herpes simplex virus types 1 and 2 HSV1 and 2, namely varicella-zoster VZV and
cytomegalovirus CMV, are among the most common pathogens worldwide. They remain in …

The use of genotypic resistance testing of herpes simplex virus types 1 and 2 (HSV-1 and
HSV-2) is increasing because the rapid availability of results significantly improves the …

Purpose To describe the clinical and virological profiles of patients with herpes simplex
keratitis (HSK) caused by acyclovir-resistant (ACV R) strains of herpes simplex virus 1 (HSV …

Purpose:: Herpes keratitis (HK) is the leading cause of cornea-derived and infection-
associated blindness in the developed world. Despite the availability of effective antivirals …

ABSTRACT A total of 302 clinical herpes simplex virus 1 (HSV-1) strains, collected over 4
decades from 1973 to 2014, were characterized retrospectively for drug resistance. All HSV …

Herpes simplex virus type 1 (HSV‐1) can establish latency in humans and easily relapse in
immunocompromised patients, with significant mortality. Treatment with acyclovir (ACV) can …

Acyclovir (ACV) and its derivatives have been highly effective for treating recurrent, lytic
infections with Herpes Simplex Virus, type 1 (HSV-1), but searches for additional antiviral …

Acyclovir is an antiviral drug frequently used in clinical practice. It is indicated for the
treatment of infections caused by herpes simplex virus and varicella zoster virus. The drug …

Purpose.: Herpes keratitis (HK) remains the leading cause of cornea-derived blindness in
the developed world, despite the availability of effective antiviral drugs. Treatment toxicity …

Here, we describe a novel reliable method to assess the significance of individual mutations
within the thymidine kinase (TK) gene of herpes simplex virus type 1 (HSV-1) to nucleoside …