Preparation, characterization, and optimization of asenapine maleate mucoadhesive nanoemulsion using Box-Behnken design: In vitro and in vivo studies for brain …

SA Kumbhar, CR Kokare, B Shrivastava… - International journal of …, 2020 - Elsevier
The tight junctions between capillary endothelial cells of the blood–brain barrier (BBB)
restricts the entry of therapeutics into the brain. Potential of the intranasal delivery tool has …

An analytical “quality by design” approach in RP-HPLC method development and validation for reliable and rapid estimation of irinotecan in an injectable formulation

N Ajitkumar Bhaskaran, L Kumar, MS Reddy… - Acta …, 2021 - hrcak.srce.hr
Sažetak The objective of the present study was to develop a robust, simple, economical and
sensitive HPLC-UV method using the “quality-by-design” approach for the estimation of …

Box–Behnken design aided optimization and validation of developed reverse phase HPLC analytical method for simultaneous quantification of dolutegravir sodium …

SP Mutalik, P Mullick, A Pandey… - Journal of …, 2021 - Wiley Online Library
A stability‐indicating reversed‐phase high‐performance liquid chromatography method for
simultaneous estimation of dolutegravir sodium and lamivudine encapsulated in the …

Asenapine Maleate-Loaded Nanostructured Lipid Carriers: Optimization and In Vitro, Ex Vivo and In Vivo Evaluations

RS Managuli, JT Wang, FN Faruqu, V Kushwah… - …, 2019 - Taylor & Francis
Aim: To prepare nanostructured lipid carriers (NLCs) loaded with asenapine maleate
(ASPM) to increase its oral bioavailability by intestinal lymphatic uptake. Materials & …

Box–behnken design-based development and validation of a reverse-phase HPLC analytical method for the estimation of paclitaxel in cationic liposomes

G Kumar, P Mullick, K Nandakumar, S Mutalik… - Chromatographia, 2022 - Springer
Stability-indicating reverse-phase HPLC analytical method for the quantification of Paclitaxel
(PTX) in the bulk and cationic liposomes was developed. The optimized method was …

Two new HPLC methods, assessed by GAPI, for simultaneous determination of four antipsychotics in pharmaceutical formulations: A comparative study

EA Abdel Hameed, ZA Abd El-Naby, A El Gindy… - Separations, 2022 - mdpi.com
Antipsychotics are widely used to treat various mental disorders. Combination therapies
were approved by the FDA to treat manic states. Quetiapine fumarate, aripiprazole …

One-pot reaction for determination of Asenapine maleate through facile complex formation with xanthine based dye: Application to content uniformity test

AA Abu-Hassan, R Ali, SM Derayea - Spectrochimica Acta Part A …, 2020 - Elsevier
Asenapine maleate was approved by the FDA for the treatment of schizophrenia and mania
or mixed episodes with bipolar I disorder. In the present article, two spectroscopic methods …

Quantitative analysis of curcumin-loaded alginate nanocarriers in hydrogels using Raman and attenuated total reflection infrared spectroscopy

L Miloudi, F Bonnier, D Bertrand, HJ Byrne… - Analytical and …, 2017 - Springer
Core-shell nanocarriers are increasingly being adapted in cosmetic and dermatological
fields, aiming to provide an increased penetration of the active pharmaceutical or cosmetic …

Analytical and bioanalytical HPLC method for simultaneous estimation of 5-fluorouracil and sonidegib

BS Padya, AR Hegde, SP Mutalik, S Biswas… - Bioanalysis, 2022 - Taylor & Francis
Aim: To develop a new sensitive RP-HPLC method for simultaneous estimation of 5-
fluorouracil (5-FU) and sonidegib (SDG). Materials & methods: Analytical and bioanalytical …

Simultaneous estimation of Apremilast and betamethasone Dipropionate in microsponge-based topical formulation using a stability indicating RP-HPLC method: A …

P Mullick, SP Mutalik, AR Hegde… - Journal of …, 2021 - academic.oup.com
A stability-indicating reverse phase high-performance liquid chromatography method was
developed and validated for simultaneous quantification of apremilast (APL) and …