[HTML][HTML] Understanding COVID-19-associated coagulopathy

EM Conway, N Mackman, RQ Warren… - Nature Reviews …, 2022 - nature.com
Abstract COVID-19-associated coagulopathy (CAC) is a life-threatening complication of
SARS-CoV-2 infection. However, the underlying cellular and molecular mechanisms driving …

[HTML][HTML] Transmissibility and transmission of respiratory viruses

NHL Leung - Nature Reviews Microbiology, 2021 - nature.com
Human respiratory virus infections lead to a spectrum of respiratory symptoms and disease
severity, contributing to substantial morbidity, mortality and economic losses worldwide, as …

[HTML][HTML] The cGAS–STING pathway drives type I IFN immunopathology in COVID-19

JD Domizio, MF Gulen, F Saidoune, VV Thacker… - Nature, 2022 - nature.com
COVID-19, which is caused by infection with SARS-CoV-2, is characterized by lung
pathology and extrapulmonary complications,. Type I interferons (IFNs) have an essential …

[HTML][HTML] SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters

PJ Halfmann, S Iida, K Iwatsuki-Horimoto, T Maemura… - Nature, 2022 - nature.com
The recent emergence of B. 1.1. 529, the Omicron variant,, has raised concerns of escape
from protection by vaccines and therapeutic antibodies. A key test for potential …

[HTML][HTML] Characterization and antiviral susceptibility of SARS-CoV-2 Omicron BA. 2

R Uraki, M Kiso, S Iida, M Imai, E Takashita, M Kuroda… - Nature, 2022 - nature.com
The recent emergence of SARS-CoV-2 Omicron (B. 1.1. 529 lineage) variants possessing
numerous mutations has raised concerns of decreased effectiveness of current vaccines …

COVID-19–related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters

GD De Melo, F Lazarini, S Levallois… - Science translational …, 2021 - science.org
Whereas recent investigations have revealed viral, inflammatory, and vascular factors
involved in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lung …

[HTML][HTML] Diverse functional autoantibodies in patients with COVID-19

EY Wang, T Mao, J Klein, Y Dai, JD Huck, JR Jaycox… - Nature, 2021 - nature.com
COVID-19 manifests with a wide spectrum of clinical phenotypes that are characterized by
exaggerated and misdirected host immune responses,,,,–. Although pathological innate …

[HTML][HTML] Long-COVID and post-COVID health complications: an up-to-date review on clinical conditions and their possible molecular mechanisms

B Silva Andrade, S Siqueira, WR de Assis Soares… - Viruses, 2021 - mdpi.com
The COVID-19 pandemic has infected millions worldwide, leaving a global burden for long-
term care of COVID-19 survivors. It is thus imperative to study post-COVID (ie, short-term) …

[HTML][HTML] Mechanisms of SARS-CoV-2 transmission and pathogenesis

AG Harrison, T Lin, P Wang - Trends in immunology, 2020 - cell.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) marks
the third highly pathogenic coronavirus to spill over into the human population. SARS-CoV-2 …

[HTML][HTML] Defining the risk of SARS-CoV-2 variants on immune protection

MM DeGrace, E Ghedin, MB Frieman, F Krammer… - Nature, 2022 - nature.com
The global emergence of many severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) variants jeopardizes the protective antiviral immunity induced after infection or …