MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

Anti-miRNA oligonucleotides: A comprehensive guide for design

JF Lima, L Cerqueira, C Figueiredo, C Oliveira… - RNA biology, 2018 - Taylor & Francis
MicroRNAs (miRNAs) are small, non-coding RNA molecules that regulate gene expression
post-transcriptionally. As a consequence of their function towards mRNA, miRNAs are …

MicroRNAs in NF-κB signaling

X Ma, LE Becker Buscaglia… - Journal of molecular cell …, 2011 - academic.oup.com
Nuclear factor κB (NF-κB) is a transcriptional factor that regulates a battery of genes that are
critical to innate and adaptive immunity, cell proliferation, inflammation, and tumor …

MicroRNAs and epigenetics

F Sato, S Tsuchiya, SJ Meltzer, K Shimizu - The FEBS journal, 2011 - Wiley Online Library
MicroRNAs (miRNAs) comprise species of short noncoding RNA that regulate gene
expression post‐transcriptionally. Recent studies have demonstrated that epigenetic …

[PDF][PDF] MicroRNAs in human diseases: from cancer to cardiovascular disease

TY Ha - Immune network, 2011 - synapse.koreamed.org
The great discovery of microRNAs (miRNAs) has revolutionized current cell biology and
medical science. miRNAs are small conserved non-coding RNA molecules that post …

[HTML][HTML] Comprehensive profiling of novel microRNA-9 targets and a tumor suppressor role of microRNA-9 via targeting IGF2BP1 in hepatocellular carcinoma

J Zhang, J Cheng, Z Zeng, Y Wang, X Li, Q Xie, J Jia… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Abstract MicroRNA-9 (miR-9) dysregulation is implicated in a variety of human malignancies
including hepatocellular carcinoma (HCC), but its role remains contradictory. In this study …

NF-κB signaling in ovarian cancer

BS Harrington, CM Annunziata - Cancers, 2019 - mdpi.com
The NF-κB signaling pathway is a master and commander in ovarian cancer (OC) that
promotes chemoresistance, cancer stem cell maintenance, metastasis and immune evasion …

Mutual regulation of microRNAs and DNA methylation in human cancers

S Wang, W Wu, FX Claret - Epigenetics, 2017 - Taylor & Francis
ABSTRACT microRNAs (miRNAs) and DNA methylation are the 2 epigenetic modifications
that have emerged in recent years as the most critical players in the regulation of gene …

Regulation of microRNAs in cancer metastasis

JMC Bouyssou, S Manier, D Huynh, S Issa… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Metastasis is a phenomenon of crucial importance in defining prognosis in patients with
cancer and is often responsible for cancer-related mortality. It is known that several steps are …

MicroRNA-9 inhibition of cell proliferation and identification of novel miR-9 targets by transcriptome profiling in breast cancer cells

SD Selcuklu, MTA Donoghue, K Rehmet… - Journal of Biological …, 2012 - ASBMB
Although underexpression of miR-9 in cancer cells is reported in many cancer types, it is
currently difficult to classify miR-9 as a tumor suppressor or an oncomir. We demonstrate that …