The “multi-functional” Ca2+ and calmodulin-dependent protein kinase, type II (CaMK-II) is an
evolutionarily conserved protein. It has been found as a single gene in the horseshoe crab …

We show that α and βCaMKII are inversely regulated by activity in hippocampal neurons in
culture: the α/β ratio shifts toward α during increased activity and β during decreased activity …

Slob is a novel protein that binds to the carboxy-terminal domain of the Drosophila
Slowpoke (dSlo) calcium-dependent potassium (K Ca) channel. A yeast two-hybrid screen …

In Drosophila melanogaster food search behaviour, groups of flies swarm around and
aggregate on patches of food. We wondered whether flies explore their environment in a …

Background Axonal transport plays a critical role in supplying materials for a variety of
neuronal functions such as morphogenetic plasticity, synaptic transmission, and cell …

Here is the first effort in a single volume to cover all of the integrative functions of calcium
signalling-how changes in intracellular calcium coordinate a variety of coherent cellular …

Development of neural circuitry relies on precise matching between correct synaptic
partners and appropriate synaptic strength tuning. Adaptive developmental adjustments may …

In the development and growth of the nervous system, as in other systems, calcium plays an
important role as a second messenger within cells. Careful spatial and temporal coding …

We investigate the mechanism of regulation of Drosophila‐soluble guanylate cyclase.
Multiple putative sites of phosphorylation for the major kinases are present on both subunits …

In order for the neuron to maintain its capacity for learning and memory it must balance local
regulation of synaptic responses to activity with global regulation of synaptic properties to …