Hydrocephalus in children

KT Kahle, AV Kulkarni, DD Limbrick, BC Warf - The lancet, 2016 - thelancet.com
Hydrocephalus is a common disorder of cerebral spinal fluid (CSF) physiology resulting in
abnormal expansion of the cerebral ventricles. Infants commonly present with progressive …

Hydrocephalus: historical analysis and considerations for treatment

A Hochstetler, J Raskin, BL Blazer-Yost - European journal of medical …, 2022 - Springer
Hydrocephalus is a serious condition that affects patients of all ages, resulting from a
multitude of causes. While the etiologies of hydrocephalus are numerous, many of the acute …

Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus

JK Karimy, J Zhang, DB Kurland, BC Theriault… - Nature medicine, 2017 - nature.com
The choroid plexus epithelium (CPE) secretes higher volumes of fluid (cerebrospinal fluid,
CSF) than any other epithelium and simultaneously functions as the blood–CSF barrier to …

Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets

JK Karimy, BC Reeves, E Damisah, PQ Duy… - Nature Reviews …, 2020 - nature.com
Hydrocephalus is the most common neurosurgical disorder worldwide and is characterized
by enlargement of the cerebrospinal fluid (CSF)-filled brain ventricles resulting from failed …

Neonatal posthemorrhagic hydrocephalus from prematurity: pathophysiology and current treatment concepts: a review

S Robinson - Journal of Neurosurgery: Pediatrics, 2012 - thejns.org
Object Preterm infants are at risk for perinatal complications, including germinal matrix–
intraventricular hemorrhage (IVH) and subsequent posthemorrhagic hydrocephalus (PHH) …

Posthaemorrhagic ventricular dilatation in the premature infant: natural history and predictors of outcome

BP Murphy, TE Inder, V Rooks, GA Taylor… - Archives of Disease in …, 2002 - fn.bmj.com
Objective: To investigate the natural history and predictors of outcome of posthaemorrhagic
ventriculomegaly in the very low birthweight (VLBW) infant. Methods: All VLBW infants …

Mechanisms of hydrocephalus after neonatal and adult intraventricular hemorrhage

J Strahle, HJL Garton, CO Maher, KM Muraszko… - Translational stroke …, 2012 - Springer
Intraventricular hemorrhage (IVH) is a cause of significant morbidity and mortality and is an
independent predictor of a worse outcome in intracerebral hemorrhage (ICH) and germinal …

Shunting outcomes in posthemorrhagic hydrocephalus: results of a Hydrocephalus Clinical Research Network prospective cohort study

JC Wellons, CN Shannon, R Holubkov… - Journal of …, 2017 - thejns.org
OBJECTIVE Previous Hydrocephalus Clinical Research Network (HCRN) retrospective
studies have shown a 15% difference in rates of conversion to permanent shunts with the …

Pediatric hydrocephalus: systematic literature review and evidence-based guidelines. Part 2: management of posthemorrhagic hydrocephalus in premature infants

CA Mazzola, AF Choudhri, KI Auguste… - Journal of …, 2014 - thejns.org
Object The objective of this systematic review and analysis was to answer the following
question: What are the optimal treatment strategies for posthemorrhagic hydrocephalus …

Neonatal interventions for preventing cerebral palsy: an overview of Cochrane Systematic Reviews

E Shepherd, RA Salam, P Middleton… - Cochrane Database …, 2018 - cochranelibrary.com
Background Cerebral palsy is an umbrella term that encompasses disorders of movement
and posture attributed to non‐progressive disturbances occurring in the developing foetal or …