RTX-KG2: a system for building a semantically standardized knowledge graph for translational biomedicine
Background Biomedical translational science is increasingly using computational reasoning
on repositories of structured knowledge (such as UMLS, SemMedDB, ChEMBL, Reactome …
on repositories of structured knowledge (such as UMLS, SemMedDB, ChEMBL, Reactome …
Exploring NCATS in-house biomedical data for evidence-based drug repurposing
Drug repurposing is a strategy for identifying new uses of approved or investigational drugs
that are outside the scope of the original medical indication. Even though many repurposed …
that are outside the scope of the original medical indication. Even though many repurposed …
Reversal gene expression assessment for drug repurposing, a case study of glioblastoma
Background Glioblastoma (GBM) is a rare brain cancer with an exceptionally high mortality
rate, which illustrates the pressing demand for more effective therapeutic options. Despite …
rate, which illustrates the pressing demand for more effective therapeutic options. Despite …