Heparan sulfate proteoglycans (HSPG) are composed of unbranched, negatively charged
heparan sulfate (HS) polysaccharides attached to a variety of cell surface or extracellular …

Respiratory syncytial virus (RSV) infection is a significant cause of hospitalization of children
in North America and one of the leading causes of death of infants less than 1 year of age …

The newly emerged human coronavirus, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), has caused a pandemic of respiratory illness. Current evidence suggests …

Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract disease in
young children and elderly people. Although the virus was isolated in 1955, an effective …

Respiratory cilia are the driving force of the mucociliary escalator, working in conjunction
with secreted airway mucus to clear inhaled debris and pathogens from the conducting …

RSV is a leading cause of respiratory tract disease in infants and the elderly. RSV has
limited therapeutic interventions and no FDA-approved vaccine. Gaps in our understanding …

Respiratory syncytial virus (RSV) is an exceptional mucosal pathogen. It specializes in
infection of the ciliated respiratory epithelium, causing disease of variable severity with little …

Respiratory syncytial virus (RSV) has eluded active vaccination efforts for more than five
decades and continues to cause substantial morbidity and mortality in infants, the …

The respiratory tract is faced daily with 10,000 L of inhaled air. While the majority of air
contains harmless environmental components, the pulmonary immune system also has to …

Cystic fibrosis is a genetic disease caused by mutations in the CFTR gene, whereas chronic
obstructive pulmonary disease (COPD) is mainly caused by environmental factors (mostly …