Reverse-zoonoses of 2009 H1N1 pandemic influenza A viruses and evolution in United States swine results in viruses with zoonotic potential

A Markin, G Ciacci Zanella, ZW Arendsee… - PLoS …, 2023 - journals.plos.org
The 2009 H1N1 pandemic (pdm09) lineage of influenza A virus (IAV) crosses interspecies
barriers with frequent human-to-swine spillovers each year. These spillovers reassort and …

Are pigs overestimated as a source of zoonotic influenza viruses?

C Hennig, A Graaf, PP Petric, L Graf… - Porcine Health …, 2022 - Springer
Background Swine influenza caused by influenza A viruses (IAV) directly affects respiratory
health and indirectly impairs reproduction rates in pigs causing production losses. In …

PARNAS: objectively selecting the most representative taxa on a phylogeny

A Markin, S Wagle, S Grover… - Systematic …, 2023 - academic.oup.com
The use of next-generation sequencing technology has enabled phylogenetic studies with
hundreds of thousands of taxa. Such large-scale phylogenies have become a critical …

Antigenic characterization and pandemic risk assessment of North American H1 influenza A viruses circulating in swine

D Venkatesh, TK Anderson, JB Kimble… - Microbiology …, 2022 - Am Soc Microbiol
The first pandemic of the 21st century was caused by an H1N1 influenza A virus (IAV)
introduced from pigs into humans, highlighting the importance of swine as reservoirs for …

Reassortment incompetent live attenuated and replicon influenza vaccines provide improved protection against influenza in piglets

A Graaf-Rau, K Schmies, A Breithaupt, K Ciminski… - npj vaccines, 2024 - nature.com
Swine influenza A viruses (swIAV) cause an economically important respiratory disease in
modern pig production. Continuous virus transmission and antigenic drift are difficult to …

Genetic and antigenic characterization of an expanding H3 influenza A virus clade in US swine visualized by Nextstrain

MN Neveau, MA Zeller, BS Kaplan, CK Souza… - Msphere, 2022 - Am Soc Microbiol
Defining factors that influence spatial and temporal patterns of influenza A virus (IAV) is
essential to inform vaccine strain selection and strategies to reduce the spread of potentially …

Immunogenicity and protective efficacy of A recombinant pichinde viral-vectored vaccine expressing influenza virus hemagglutinin antigen in pigs

S Kumari, J Chaudhari, Q Huang, P Gauger… - Vaccines, 2022 - mdpi.com
Influenza A virus of swine (IAV-S) is an economically important swine pathogen. The IAV-S
hemagglutinin (HA) surface protein is the main target for vaccine development. In this study …

Pathogenesis and Transmission Assessment of 3 Swine-Origin Influenza A (H3N2) Viruses With Zoonotic Risk to Humans Isolated in the United States, 2017–2020

X Sun, JA Belser, JA Pulit-Penaloza… - The Journal of …, 2024 - academic.oup.com
The sporadic occurrence of human infections with swine-origin influenza A (H3N2) viruses
and the continual emergence of novel A (H3N2) viruses in swine herds underscore the …

Sequence-Based Antigenic Analyses of H1 Swine Influenza A Viruses from Colombia (2008–2021) Reveals Temporal and Geographical Antigenic Variations

AF Ospina-Jimenez, AP Gomez, MA Rincon-Monroy… - Viruses, 2023 - mdpi.com
Swine influenza is a respiratory disease that affects the pork industry and is a public health
threat. It is caused by type A influenza virus (FLUAV), which continuously undergoes genetic …

[PDF][PDF] Antigenic switch potential of influenza D virus

AB Hejran, K Saken, R Afghan… - Asia Pacific Journal of …, 2024 - researchgate.net
The antigenic variability of Influenza D virus (IDV), a recently identified pathogen with
significant implications for livestock and zoonotic diseases, presents unique challenges in …