Over the past few decades, RNA sequencing has significantly progressed, becoming a
paramount approach for transcriptome profiling. The revolution from bulk RNA sequencing …

With recent advances in high-throughput next-generation sequencing, it is possible to
describe the regulation and expression of genes at multiple levels. An assay for transposase …

Molecular analyses of normal and diseased cells give insight into changes in gene
expression and help in understanding the background of pathophysiological processes …

Motivation Single-cell RNA sequencing (scRNA-seq) has revolutionized biological sciences
by revealing genome-wide gene expression levels within individual cells. However, a critical …

Transcriptome profiling has become routine in studies of many biological processes.
However, the favored approaches such as short-read Illumina RNA sequencing are giving …

Background Genetic disposition is considered critical for identifying subjects at high risk for
disease development. Investigating disease-causing and high and low expressed genes …

Advances in next generation sequencing (NGS) technologies resulted in a broad array of
large-scale gene expression studies and an unprecedented volume of whole messenger …

To better understand the molecular mechanisms of intracranial aneurysm (IA) pathogenesis,
we used gene coexpression networks to identify hub genes and functional pathways …

Abstract Background RNA sequencing (RNA-Seq) in its varied forms has become an
indispensable tool for analyzing differential gene expression and thus characterization of …

Ribonucleic acids (RNAs) are fundamental molecules that control regulation and expression
of the genome and therefore the function of a cell. Robust analysis and quantification of RNA …