[HTML][HTML] Streptococcal superantigens: biological properties and potential role in disease

T Proft, JD Fraser - 2016 - europepmc.org
Superantigens (SAgs) are a family of highly potent mitogens that share the ability to trigger
excessive stimulation of human and other mammalian T lymphocytes. This leads to a …

[HTML][HTML] Streptococcus pyogenes Superantigens: Biological properties and potential role in disease

T Proft, JD Fraser - … Basic Biology to Clinical Manifestations [Internet …, 2022 - ncbi.nlm.nih.gov
Superantigens (SAgs) are a family of highly potent mitogens that share the ability to trigger
excessive stimulation of human and other mammalian T lymphocytes. This leads to a …

Inhibition of squamous cancer growth in a mouse model by Staphylococcal enterotoxin B-triggered Th9 cell expansion

BP Miao, RS Zhang, HJ Sun, YP Yu, T Chen… - Cellular & molecular …, 2017 - nature.com
Currently, therapy for squamous cancer (SqC) is unsatisfactory. Staphylococcal enterotoxin
B (SEB) has strong immune regulatory activity. This study tests the hypothesis that SEB …

Inhibition of the superantigenic activities of Staphylococcal enterotoxin A by an aptamer antagonist

K Wang, D Wu, Z Chen, X Zhang, X Yang, CJ Yang… - Toxicon, 2016 - Elsevier
Staphylococcal enterotoxin A (SEA) is an important component of Staphylococcus aureus
pathogenesis. SEA induces T lymphocytes activation and proliferation, resulting in the …

Two common structural motifs for TCR recognition by staphylococcal enterotoxins

KEJ Rödström, P Regenthal, C Bahl, A Ford… - Scientific Reports, 2016 - nature.com
Superantigens are toxins produced by Staphylococcus aureus, called staphylococcal
enterotoxins (abbreviated SEA to SEU). They can cross-link the T cell receptor (TCR) and …

[PDF][PDF] Bacterial superantigens and superantigen-like toxins

RJ Langley, JD Fraser, T Proft - The Comprehensive Sourcebook …, 2015 - researchgate.net
The term superantigen (SAg) was coined in 1989 in the research group of Philippa Marrack
and John Kappler and describes a group of proteins with extremely high potency to …

Multiplex Detection of Seven Staphylococcal Enterotoxins Using Liquid Chromatography–Mass Spectrometry Combined with a Novel Capture Molecule

J Lv, T Liu, X Fang, S Han, L Dong, J Li, J Wang… - Separations, 2024 - mdpi.com
Food poisoning caused by Staphylococcal enterotoxins (SEs) is prevalent globally, making
efficient detection of these toxins very important. Traditionally, liquid chromatography–mass …

Induction of specific T helper-9 cells to inhibit glioma cell growth

H Zheng, B Yang, D Xu, W Wang, J Tan, L Sun… - …, 2016 - pmc.ncbi.nlm.nih.gov
The effects of Staphylococcal enterotoxin B (SEB) on regulation of immune response have
been recognized; whether SEB can enhance the effects of immunotherapy on glioma …

[图书][B] Streptococcal superantigens

A Babbar, A Babbar - 2015 - Springer
This book starts with a basic knowledge about Streptococcus pyogenes as a pathogen. It
elucidates briefly about the array of virulence factors possessed by Streptococcus pyogenes …

A Multiplex assay for detection of staphylococcal and streptococcal exotoxins

P Sharma, N Wang, AS Chervin, CL Quinn, JD Stone… - Plos one, 2015 - journals.plos.org
Staphylococcal and streptococcal exotoxins, also known as superantigens, mediate a range
of diseases including toxic shock syndrome, and they exacerbate skin, pulmonary and …