[HTML][HTML] Microbiome—Stealth Regulator of Breast Homeostasis and Cancer Metastasis

S Furuta - Cancers, 2024 - mdpi.com
Simple Summary It has long been known that breast tumors harbor various types of
microbes. However, it was little known where these tumor-resident microbes came from and …

Rhamnolipids know-how: looking for strategies for its industrial dissemination

RB Lovaglio, VL Silva, H Ferreira, R Hausmann… - Biotechnology …, 2015 - Elsevier
Despite the numerous advantages of biosurfactants, such as low toxicity, biodegradability
and high stability, these compounds are not widely used because of the high cost of …

Trace incorporation of heavy water reveals slow and heterogeneous pathogen growth rates in cystic fibrosis sputum

SH Kopf, AL Sessions, ES Cowley… - Proceedings of the …, 2016 - National Acad Sciences
Effective treatment for chronic infections is undermined by a significant gap in understanding
of the physiological state of pathogens at the site of infection. Chronic pulmonary infections …

Initiation of fatty acid biosynthesis in Pseudomonas putida KT2440

KJ McNaught, E Kuatsjah, M Zahn, ÉT Prates… - Metabolic …, 2023 - Elsevier
Deciphering the mechanisms of bacterial fatty acid biosynthesis is crucial for both the
engineering of bacterial hosts to produce fatty acid-derived molecules and the development …

Pseudomonas aeruginosa responds to exogenous polyunsaturated fatty acids (PUFAs) by modifying phospholipid composition, membrane permeability, and …

LY Baker, CR Hobby, AW Siv, WC Bible, MS Glennon… - BMC microbiology, 2018 - Springer
Background Pseudomonas aeruginosa, a common opportunistic pathogen, is known to
cause infections in a variety of compromised human tissues. An emerging mechanism for …

The impaired quorum sensing response of Pseudomonas aeruginosa MexAB‐OprM efflux pump overexpressing mutants is not due to non‐physiological efflux of 3 …

M Alcalde‐Rico, J Olivares‐Pacheco… - Environmental …, 2020 - Wiley Online Library
Multidrug (MDR) efflux pumps are ancient and conserved molecular machineries with
relevant roles in different aspects of the bacterial physiology, besides antibiotic resistance. In …

Molecular modelling study and antibacterial evaluation of diphenylmethane derivatives as potential fabi inhibitors

S Hasan, K Kayed, R Ghemrawi, NA Bataineh… - Molecules, 2023 - mdpi.com
The need for new antibiotics has become a major worldwide challenge as bacterial strains
keep developing resistance to the existing drugs at an alarming rate. Enoyl-acyl carrier …

Fatty acid biosynthesis in Pseudomonas aeruginosa is initiated by the FabY class of β-ketoacyl acyl carrier protein synthases

Y Yuan, M Sachdeva, JA Leeds… - Journal of …, 2012 - Am Soc Microbiol
The prototypical type II fatty acid synthesis (FAS) pathway in bacteria utilizes two distinct
classes of β-ketoacyl synthase (KAS) domains to assemble long-chain fatty acids, the KASIII …

Micafungin effect on Pseudomonas aeruginosa metabolome, virulence and biofilm: potential quorum sensing inhibitor

DM Hijazi, LA Dahabiyeh, S Abdelrazig, DA Alqudah… - Amb Express, 2023 - Springer
The prevalence of antibiotic resistance in Pseudomonas aeruginosa places a heavy burden
on the health care sectors urging the need to find alternative, non-antibiotic strategies. The …

Metabolomics responses and tolerance of Pseudomonas aeruginosa under acoustic vibration stress

N Vinayavekhin, T Wattanophas, MF Murphy… - Plos one, 2024 - journals.plos.org
Sound has been shown to impact microbial behaviors. However, our understanding of the
chemical and molecular mechanisms underlying these microbial responses to acoustic …