A framework for developing sex-specific engineered heart models

R Lock, H Al Asafen, S Fleischer, M Tamargo… - Nature Reviews …, 2022 - nature.com
The convergence of tissue engineering and patient-specific stem cell biology has enabled
the engineering of in vitro tissue models that allow the study of patient-tailored treatment …

Bacterial cellulose and ECM hydrogels: An innovative approach for cardiovascular regenerative medicine

IGR Silva, BTS Pantoja, GHDR Almeida… - International Journal of …, 2022 - mdpi.com
Cardiovascular diseases are considered the leading cause of death in the world, accounting
for approximately 85% of sudden death cases. In dogs and cats, sudden cardiac death …

Biohybrid oxidized alginate/myocardial extracellular matrix injectable hydrogels with improved electromechanical properties for cardiac tissue engineering

A Mousavi, S Mashayekhan, N Baheiraei… - International journal of …, 2021 - Elsevier
Injectable hydrogels which mimic the physicochemical and electromechanical properties of
cardiac tissue is advantageous for cardiac tissue engineering. Here, a newly-developed in …

Electroactive graphene oxide‐incorporated collagen assisting vascularization for cardiac tissue engineering

MH Norahan, M Amroon… - … research Part A, 2019 - Wiley Online Library
The application of a cardiac patch over the epicardial surface has shown positive effects in
protecting cardiac function postinfarction. Electroactive patches could enhance electrical …

Adhesive tissue engineered scaffolds: mechanisms and applications

S Chen, CJ Gil, L Ning, L Jin, L Perez… - … in Bioengineering and …, 2021 - frontiersin.org
A variety of suture and bioglue techniques are conventionally used to secure engineered
scaffold systems onto the target tissues. These techniques, however, confront several …

Murine neonatal cardiac regeneration depends on Insulin-like growth factor 1 receptor signaling

T Schuetz, T Dolejsi, E Beck, F Fugger, A Bild… - Scientific Reports, 2024 - nature.com
Unlike adult mammals, the hearts of neonatal mice possess the ability to completely
regenerate from myocardial infarction (MI). This observation has sparked vast interest in …

Cardiovascular tissue bioprinting: physical and chemical processes

JB Hu, ML Tomov, JW Buikema, C Chen… - Applied Physics …, 2018 - pubs.aip.org
Three-dimensional (3D) cardiac tissue bioprinting occupies a critical crossroads position
between the fields of materials engineering, cardiovascular biology, 3D printing, and rational …

Human iPSCs and genome editing technologies for precision cardiovascular tissue engineering

EKN Gähwiler, SE Motta, M Martin… - Frontiers in Cell and …, 2021 - frontiersin.org
Induced pluripotent stem cells (iPSCs) originate from the reprogramming of adult somatic
cells using four Yamanaka transcription factors. Since their discovery, the stem cell (SC) field …

Patient‐Specific 3D Bioprinted Models of Developing Human Heart

AD Cetnar, ML Tomov, L Ning, B Jing… - Advanced …, 2021 - Wiley Online Library
The heart is the first organ to develop in the human embryo through a series of complex
chronological processes, many of which critically rely on the interplay between cells and the …

Ccn2a is an injury-induced matricellular factor that promotes cardiac regeneration in zebrafish

D Mukherjee, G Wagh, MH Mokalled… - …, 2021 - journals.biologists.com
The ability of zebrafish to heal their heart after injury makes them an attractive model for
investigating the mechanisms governing the regenerative process. In this study, we show …