[HTML][HTML] Ligand-dependent CD36 functions in cancer progression, metastasis, immune response, and drug resistance

L Xia, Z Zhou, X Chen, W Luo, L Ding, H Xie… - Biomedicine & …, 2023 - Elsevier
CD36, a multifunctional glycoprotein, has been shown to play critical roles in tumor initiation,
progression, metastasis, immune response, and drug resistance. CD36 serves as a receptor …

Hidden features: CD36/SR-B2, a master regulator of macrophage phenotype/function through metabolism

Y Chen, X Zhang, S Huang, M Febbraio - Frontiers in Immunology, 2024 - frontiersin.org
Once thought to be in a terminally differentiated state, macrophages are now understood to
be highly pliable, attuned and receptive to environmental cues that control and align …

Integrated multi-omics analysis and machine learning developed diagnostic markers and prognostic model based on Efferocytosis-associated signatures for septic …

X Li, S Jiang, B Wang, S He, X Guo, J Lin, Y Wei - Clinical Immunology, 2024 - Elsevier
Septic cardiomyopathy (SCM) is characterized by an abnormal inflammatory response and
increased mortality. The role of efferocytosis in SCM is not well understood. We used …

Targeting CD36 With EP 80317 Reduces Remote Inflammatory Response to Hind Limb Ischemia‐Reperfusion in Mice

H Elimam, J Gauvin, DN Huynh… - … of Biochemical and …, 2024 - Wiley Online Library
Reperfusion of ischemic skeletal muscle triggers oxidative stress and an immediate
inflammatory reaction, leading to damage of distant organs such as the lungs. The …

Convergent Solution-Phase Synthesis of a Cyclic Azapeptide CD36 Modulator

NM Mesli, JC Fonseca, P Chauhan, YG Ramos… - 2024 - sciforum.net
Cyclic azapeptide cluster of differentiation-36 receptor (CD36) modulator 298 has exhibited
biomedical potential for treating diseases implicating macrophage-driven inflammation. 1, 2 …